Table 5.

Tox functional categories involving renal and urological system abnormalities for differentially expressed proteins.

Categories	Functions	Diseases or functions annotation	p value	Molecules	# molecules
Kidney failure	Failure	Failure of kidney	0.00237	C3,F10,SERPINC1,LCN2	4
Kidney failure	End stage renal disease	End stage renal disease	0.00318	C3,F10,SERPINC1	3
Kidney failure	Acute tubular necrosis	Acute tubular necrosis	0.00745	LCN2	1
Glomerular injury	C3 glomerulopathy	C3 glomerulopathy	0.00745	C3	1
Nephrosis	Nephrosis	Nephrosis	0.00861	C3,F10,SERPINC1	3
Kidney failure and renal damage	Ischemic acute renal failure	Ischemic acute renal failure	0.00992	LCN2	1
Glomerular injury, renal inflammation, renal nephritis	Membranoproliferative glomerulonephritis	Membranoproliferative glomerulonephritis	0.00992	C3	1
Nephrosis	Steroid-dependent nephrotic syndrome	Steroid-dependent nephrotic syndrome	0.0295	C3	1
Glomerular injury, renal inflammation, and renal nephritis	IgA nephropathy	IgA nephropathy	0.0882	C3	1
Glomerular injury, renal inflammation, and renal nephritis	Lupus nephritis	Lupus nephritis	0.412	C3	1
Renal necrosis/cell death	Apoptosis	Apoptosis of kidney cell lines	0.478	RBP4	1