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. 2022 May 16;27(3):223–228. doi: 10.6065/apem.2142210.105

Table 2.

Vitamin B12 level changes across time while on metformin treatment

Duration of treatment Vitamin B12 level (pg/mL)
P-value (2-tailed)
MD (95% CI) SEM
0 Month 0 N/A Reference group
6 Months -31.78 (-15.34 to 78.91) 23.85 0.185
12 Months -4.92 (-49.06 to 58.90) 27.32 0.857
24 Months -24.51 (-24.25 to 73.26) 24.69 0.322
36 Months -48.28 (-7.44 to 103.99) 28.16 0.089

MD, mean difference; CI, confidence interval; SEM, standard error of the mean; N/A, not available.