Table 5.
Changes in vitamin B12 across time intervals and levels of compliance
| Treatment group | Vitamin B12 level (pg/mL) |
P-value (2-tailed) | ||
|---|---|---|---|---|
| Mean±SD | MD (95% CI) | SED | ||
| High dose with good compliance | ||||
| Baseline | 571.29±137.66 | 0 | N/A | N/A |
| 6 Months | 536.44±59.89 | -34.84 (-74.17 to 143.85) | 50.83 | 0.504 |
| 12 Months | 524.75±125.00 | -46.54 (-99.93 to 193.00) | 67.80 | 0.505 |
| 24 Months | 429.56±97.06 | -141.73 (16.12 to 267.34) | 58.56 | 0.030* |
| 36 Months | 398.75±80.49 | -172.54 (48.86 to 296.21) | 57.25 | 0.010* |
| Low dose with good compliance | ||||
| Baseline | 507.09±130.68 | 0 | N/A | N/A |
| 6 Months | 486.78±137.96 | -20.30 (-39.91 to 80.52) | 30.25 | 0.504 |
| 12 Months | 521.52±181.34 | 14.44 (-87.02 to 58.15) | 36.45 | 0.693 |
| 24 Months | 488.61±141.19 | -18.48 (-44.10 to 81.05) | 31.41 | 0.558 |
| 36 Months | 495.48±150.07 | -11.61 (-61.27 to 84.48) | 36.41 | 0.751 |
| Low dose with poor compliance | ||||
| Baseline | 549.83±225.24 | 0 | N/A | N/A |
| 6 Months | 539.45±180.51 | -10.38 (-167.72 to 188.47) | 56.64 | 0.905 |
| 12 Months | 560.42±229.68 | 10.58 (-203.17 to 182.01) | 92.86 | 0.910 |
| 24 Months | 564.90±180.31 | 15.07 (-162.70 to 132.57) | 72.29 | 0.836 |
| 36 Months | 562.58±192.37 | 12.75 (-190.08 to 164.58) | 85.51 | 0.883 |
SD, standard deviation; MD, mean difference; CI, confidence interval; SED, standard error difference; N/A, not available.
*
P<0.05, statistically significant differences.