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. 2022 Sep 23;13:975327. doi: 10.3389/fendo.2022.975327

Table 1.

Baseline characteristics of participants stratified by the quartile of the WHR.

Total population Q1 Q2 Q3 Q4 P value
N 6253 1719 1530 1717 1287
Age, years 58.44 ± 13.11 54.95 ± 12.91 57.63 ± 13.28 59.94 ± 12.84 62.07 ± 12.24 < 0.001
Sex, male, n (%) 2891 (46.2) 209 (12.2) 597 (39.0) 1078 (62.8) 1007 (78.2) < 0.001
Race, n (%) < 0.001
 Non-Hispanic white 3151 (50.4) 924 (53.8) 736 (48.1) 853 (49.7) 638 (49.6)
 Non-Hispanic black 1392 (22.3) 443 (25.8) 414 (27.1) 349 (20.3) 186 (14.5)
 Mexican-American 1440 (23.0) 261 (15.2) 314 (20.5) 440 (25.6) 425 (33.0)
 Others 270 (4.3) 91 (5.3) 66 (4.3) 75 (4.4) 38 (3.0)
Smoking, n (%) 3415 (54.6) 740 (43.0) 796 (52.0) 1032 (60.1) 847 (65.8) < 0.001
Diabetes, n (%) 618 (9.9) 85 (5.0) 128 (8.4) 200 (11.6) 205 (16.0) < 0.001
Hypertension, n (%) 2021 (32.5) 410 (23.9) 485 (31.8) 617 (36.1) 509 (39.8) < 0.001
Body mass index, kg/m2 27.60± 5.49 26.03 ± 6.07 27.24 ± 5.68 28.02 ± 4.74 29.60 ± 4.60 < 0.001
Pulse, bpm 75.27 ± 12.23 74.38 ± 11.35 75.18 ± 12.41 75.45 ± 12.19 76.32 ± 13.12 < 0.001
SBP, mmHg 131.14 ± 18.95 124.87 ± 18.35 131.10 ± 19.43 134.00 ± 18.41 135.75 ± 17.60 < 0.001
DBP, mmHg 58.11 ± 7.08 58.44 ± 6.59 58.08 ± 7.03 57.93 ± 7.44 57.95 ± 7.30 0.143
Triglycerides, mg/dL 127.0 (90.0, 184.0) 99 (74.0, 142.0) 122.0 (88.0, 168.0) 141.0 (102.0, 202.0) 165.0 (113.0, 241.0) < 0.001
Total cholesterol, mg/dL 217.75 ± 43.06 212.49 ± 41.82 219.62 ± 43.61 220.93 ± 42.91 218.30 ± 43.63 < 0.001
LDL−C, mg/dL 136.50 ± 38.50 130.04 ± 36.84 138.01 ± 39.60 140.47 ± 38.15 138.25 ± 38.87 < 0.001
HDL−C, mg/dL 51.51 ± 16.47 58.41 ± 16.65 53.43 ± 16.56 48.11 ± 14.97 44.48 ± 13.78 < 0.001
Fibrinogen, mg/dL 309.48 ± 85.12 301.05 ± 78.91 305.83 ± 84.96 312.89 ± 87.01 320.33 ± 89.25 < 0.001
C-reactive protein, mg/dL 0.21 (0.21, 0.50) 0.21 (0.21, 0.40) 0.21 (0.21, 0.44) 0.21 (0.21, 0.50) 0.21 (0.21, 0.60) < 0.001
Creatinine, mg/dL 1.09 ± 0.35 1.01 ± 0.34 1.07 ± 0.20 1.13 ± 0.32 1.18 ± 0.49 < 0.001
Uric acid, mg/dL 5.40 ± 1.46 4.67 ± 1.26 5.33 ± 1.39 5.69 ± 1.39 6.07 ± 1.44 < 0.001
BUN, mg/dL 15.17 ± 5.52 14.04 ± 5.36 15.02 ± 4.85 15.59 ± 6.00 16.30 ± 5.52 < 0.001
FPG, mg/dL 95.0 (88.0, 105.0) 91.0 (86.0, 99.0) 94.0 (88.0, 103.0) 97.0 (89.0, 107.0) 100.0 (91.0, 114.0) < 0.001
HbA1c, % 5.74 ± 1.23 5.45 ± 0.88 5.70 ± 1.16 5.84 ± 1.32 6.05 ± 1.46 < 0.001
CIIS 2.2 (0, 8.8) 1.4 (0, 7.3) 1.5 (0, 7.6) 2.6 (0, 9.6) 3.7 (0, 10.7) < 0.001
SC-MI, n (%) 1342 (21.5) 294 (17.1) 281 (18.4) 407 (23.7) 360 (28.0) < 0.001

Data are expressed as mean ± SD, median (interquartile range), or n (%).

WHR, waist-hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; BUN, blood urea nitrogen; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; CIIS, cardiac infarction/injury score; SC-MI, subclinical myocardial injury.