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. 2022 Sep 13:10.1002/jmv.28122. Online ahead of print. doi: 10.1002/jmv.28122

FIGURE 4.

FIGURE 4

Immunopathology in long COVID: Immunopathology in long COVID is studied at different biological levels. At the physiological levels, individuals recovering from acute SARS‐CoV‐2 infection have been complaining about brain fog, headache, fatigue, cough, and so forth, for a prolonged period. At the organ levels, in infected patients, there have been reports of long‐term neuro‐and gastroinflammation. In some individuals, there have been incidences of liver and heart conditions. However, the cellular insight into this chronic illness remains poorly understood. Some of the recent reports have suggested the presence of viral remnants, prolonged systemic or tissue inflammatory responses, and/or the presence of autoantibodies may contribute to the disease etiology. COVID‐19, coronavirus disease 2019; IFN, interferon; SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2.