Flow‐chart of pregnant people with SARS‐CoV‐2 infection included in this analysis, SET‐NET, 22 Jurisdictionsa, January 25, 2020–December 31, 2020, reported as of December 3, 2021. (a) 22 jurisdictions included in this analysis are Arkansas, City of Chicago, Georgia, City of Houston, Iowa, Illinois (excluding Chicago), Massachusetts, Maryland, Michigan, Minnesota, Missouri, Nebraska, New Hampshire, New Jersey, New York (excluding New York City), Pennsylvania (excluding Philadelphia), Philadelphia County, Puerto Rico, South Carolina, Tennessee, U.S. Virgin Islands, and Washington. (b) 15 jurisdictions included for birth defects subanalysis are Arkansas, City of Chicago, City of Houston, Iowa, Illinois (excluding Chicago), Minnesota, Missouri, Nebraska, New Jersey, New York State (excluding New York City), Pennsylvania, Philadelphia, Puerto Rico, South Carolina, and Washington. (c) 18 jurisdictions included for COVID‐19 treatment subanalysis are Arkansas, City of Chicago, City of Houston, Illinois (excluding Chicago), Massachusetts, Michigan, Minnesota, Missouri, Nebraska, New Hampshire, New Jersey, New York (excluding New York City), Pennsylvania, Puerto Rico, South Carolina, Tennessee, U.S. Virgin Islands, and Washington.