TABLE 1.
Demographic and pregnancy characteristics, underlying medical conditions, and SARS‐CoV‐2 infection characteristics of pregnant people with a known pregnancy outcome, by trimester of infection, SET‐NET, 22 Jurisdictions, January 25, 2020–December 31, 2020
| Total n (%) | First trimester (<14 weeks) n (%) a | Second trimester (14–27 weeks) n (%) b | Third trimester (28–42 weeks) n (%) | |
|---|---|---|---|---|
| Total | 35,200 | 6,458 (18.3) | 10,848 (30.8) | 17,894 (50.8) |
| Age at infection, years c | 35,193 | 6,457 | 10,846 | 17,890 |
| Median (IQR Q1‐Q3) | 29.1 (23.0–33.2) | 28.8 (25.0–32.6) | 29.4 (25.4–33.2) | 28.9 (24.8–33.3) |
| <20 | 1821 (5.2) | 304 (4.7) | 497 (4.6) | 1,020 (5.7) |
| 20–24 | 6,923 (19.7) | 1,306 (20.2) | 1948 (18.0) | 3,669 (20.5) |
| 25–29 | 10,891 (30.9) | 2,119 (32.8) | 3,411 (31.4) | 5,361 (30.0) |
| 30–34 | 9,715 (27.6) | 1819 (28.2) | 3,162 (29.2) | 4,734 (26.5) |
| 35–39 | 4,742 (13.5) | 747 (11.6) | 1,506 (13.9) | 2,489 (13.9) |
| 40+ | 1,101 (3.1) | 162 (2.5) | 322 (3.0) | 617 (3.4) |
| Unknown | 7 (0.0) | 1 (0.0) | 2 (0.0) | 4 (0.0) |
| Race/ethnicity c | 34,541 | 6,356 | 10,650 | 17,535 |
| Hispanic or Latina | 11,127 (32.2) | 1763 (27.7) | 3,151 (29.6) | 6,213 (35.4) |
| Asian, non‐Hispanic | 1,310 (3.8) | 225 (3.5) | 402 (3.8) | 683 (3.9) |
| Black, non‐Hispanic | 6,143 (17.8) | 1,057 (16.6) | 1829 (17.2) | 3,257 (18.6) |
| White, non‐Hispanic | 14,758 (42.7) | 3,132 (49.3) | 4,906 (46.1) | 6,720 (38.3) |
| Multiple or other d race, non‐Hispanic | 1,203 (3.5) | 179 (2.8) | 362 (3.4) | 662 (3.8) |
| Unknown | 659 (1.9) | 102 (1.6) | 198 (1.8) | 359 (2.0) |
| Health insurance c | 30,306 | 5,482 | 9,232 | 15,592 |
| Private | 13,935 (46.0) | 2,815 (51.3) | 4,621 (50.1) | 6,499 (41.7) |
| Medicaid | 14,787 (48.8) | 2,426 (44.3) | 4,195 (45.4) | 8,166 (52.4) |
| Other e | 917 (3.0) | 173 (3.2) | 278 (3.0) | 466 (3.0) |
| Self‐pay/none | 667 (2.2) | 68 (1.2) | 138 (1.5) | 461 (3.0) |
| Unknown | 4,894 (13.9) | 976 (15.1) | 1,616 (14.9) | 2,302 (12.9) |
| Underlying medical conditions c | 34,256 | 6,360 | 10,527 | 17,369 |
| Any underlying condition | 14,597 (42.6) | 2,499 (39.3) | 4,315 (41.0) | 7,783 (44.8) |
| Obesity (pre‐pregnancy BMI ≥30 kg/m2) | 11,281 (32.9) | 2,152 (33.8) | 3,715 (35.3) | 5,414 (31.2) |
| Chronic lung disease | 1,159 (3.4) | 187 (2.9) | 379 (3.6) | 593 (3.4) |
| Diabetes mellitus | 670 (2.0) | 109 (1.7) | 238 (2.3) | 323 (1.9) |
| Chronic hypertension | 1,621 (4.7) | 327 (5.1) | 587 (5.6) | 707 (4.1) |
| Cardiovascular disease | 401 (1.2) | 51 (0.8) | 114 (1.1) | 236 (1.4) |
| Immunosuppression | 175 (0.5) | 31 (0.5) | 63 (0.6) | 81 (0.5) |
| Other f | 1,312 (3.8) | 200 (3.1) | 378 (3.6) | 734 (4.2) |
| Pregnancy complications c | 6,062 | 1,119 | 1995 | 2,948 |
| Gestational hypertension | 3,025 (9.1) | 578 (9.4) | 975 (9.5) | 1,472 (8.8) |
| Gestational diabetes mellitus | 3,503 (10.6) | 630 (10.2) | 1,172 (11.4) | 1701 (10.2) |
| Prenatal care c | 33,796 | 6,326 | 10,474 | 16,996 |
| Yes (trimester initiated) g | 33,221 (98.3) | 6,241 (98.7) | 10,350 (98.8) | 16,630 (97.8) |
| First trimester | 22,471 (67.6) | 4,151 (66.5) | 7,404 (71.5) | 10,916 (65.6) |
| Second trimester | 5,073 (15.3) | 848 (13.6) | 1,355 (13.1) | 2,870 (17.3) |
| Third trimester | 913 (2.7) | 111 (1.8) | 210 (2.0) | 592 (3.6) |
| Unknown trimester | 4,764 (14.3) | 1,131 (18.1) | 1,381 (13.3) | 2,252 (13.5) |
| No | 575 (1.7) | 85 (1.4) | 124 (1.2) | 366 (2.2) |
| Unknown | 1,404 (4.0) | 132 (2.0) | 374 (3.4) | 898 (5.0) |
Trimester of SARS‐CoV‐2 infection is based on calculated date of last menstrual period and date of first positive COVID‐19 laboratory result.
Participating jurisdictions included Arkansas, City of Chicago, Georgia, City of Houston, Iowa, Illinois (excluding Chicago), Massachusetts, Maryland, Michigan, Minnesota, Missouri, Nebraska, New Hampshire, New Jersey, New York (excluding New York City), Pennsylvania (excluding Philadelphia), Philadelphia County, Puerto Rico, South Carolina, Tennessee, U.S. Virgin Islands, and Washington.
Totals for each of the demographic and pregnancy characteristics do not include “Unknown.”
Other race includes Native Hawaiian or other Pacific Islander, American Indian or Alaska Native, and self‐reported as other.
Other insurance includes Indian Health Service, CHAMPUS or TRICARE; other government (federal, state, or local), or charity.
Other underlying medical conditions includes chronic renal disease, chronic liver disease, psychological/psychiatric condition, disability, and autoimmune condition.
Trimester of prenatal care initiation was derived from the date of first prenatal care visit and calculated last menstrual period.