Table 1.
Baseline clinical characteristics of 188 elderly patients with AF at high risk of thromboembolism and bleeding.
| Characteristic | Patients with AF (n = 188) |
|---|---|
| Age, mean (SD) (years) | 87.6 (7.7) |
| Male, n (%) | 174 (92.55) |
| Systolic blood pressure, mean (SD) (mmHg) | 133.82 (13.65) |
| Diastolic blood pressure, mean (SD) (mmHg) | 69.91 (10.62) |
| Smoking history, n (%) | 90 (47.87) |
| Drinking history, n (%) | 88 (46.81) |
| Type of AF, n (%) | |
| New onset AF, n (%) | 7 (3.72) |
| Paroxysmal AF, n (%) | 117 (62.23) |
| Persistent AF, n (%) | 13 (6.91) |
| Permanent AF, n (%) | 51 (27.13) |
| Comorbidities | |
| Hypertension, n (%) | 135 (71.81) |
| Coronary heart disease, n (%) | 143 (76.06) |
| Old myocardial infarction, n (%) | 38 (20.21) |
| Hyperlipidemia, n (%) | 41 (21.81) |
| Type 2 diabetes, n (%) | 64 (34.04) |
| Congestive heart failure, n (%) | 44 (23.40) |
| Stroke, n (%) | 84 (44.68) |
| Peripheral vascular disease, n (%) | 26 (13.83) |
| Renal dysfunction, n (%) | 48 (25.53) |
| Liver dysfunction, n (%) | 4 (2.13) |
| Anemia, n (%) | 41 (21.81) |
| Past bleeding history, n (%) | 39 (65.42) |
| Current bleeding, n (%) | 15 (7.99) |
| Risk of fall, n (%) | 68 (36.17) |
| CHA2DS2-VASc, mean (SD) | 5.1 (1.6) |
| HAS-BLED, mean (SD) | 3.4 (1.2) |
| Anticoagulation therapy | |
| Warfarin, n (%) | 10 (5.32) |
| Rivaroxaban, n (%) | 25 (13.30) |
| Clopidegrel, n (%) | 78 (41.49) |
| Aspirin, n (%) | 74 (39.36) |
AF, atrial fibrillation; SD, standard deviation; CHA2DS2-VASc: congestive heart failure, hypertension, age 75 years (doubled), diabetes mellitus, stroke or transient ischemic attack (doubled), vascular disease, age 65 to 74 years, and female sex; HAS-BLED: hypertension, abnormal renal/liver function, stroke, bleeding history or predisposition, labile international normalized ratio, elderly (65 years), drugs/alcohol concomitance.