TABLE 1.
Demographics of patients and characteristics of thromboembolic events after Ad.26.COV2.S vaccine (VAERS overview February 27, 2021–February 28, 2022)
| Age a (years) | |
|---|---|
| n | 3157 |
| Mean (standard deviation) | 55.3 (16.3) |
| Median (interquartile range) | 56 (44–66) |
| Sex | |
| Female | 1938 (51.1%) |
| Male | 1646 (43.4%) |
| Not reported | 206 (5.4%) |
| Race | |
| White | 1966 (51.9%) |
| Black | 305 (8.0%) |
| Mixed race | 101 (2.7%) |
| Other race | 93 (2.5%) |
| Not reported | 1325 (35.0%) |
| Ethnicity | |
| Non‐Hispanic | 1910 (50.4%) |
| Hispanic | 222 (5.9%) |
| Not reported | 1658 (43.7%) |
| Time to onset b (days) | |
| n | 3043 |
| Mean (standard deviation) | 29.7 (51.0) |
| Median (interquartile range) | 12 (3–28) |
| Seriousness c and reported outcomes | |
| Serious | 2892 (76.3%) |
| Hospitalized | 1965 (51.9%) |
| Life‐threatening | 841 (22.2%) |
| Died | 421 (11.1%) |
| Permanent disability | 398 (10.5%) |
| Hospitalization prolonged | 21 (0.6%) |
| Congenital anomaly | 7 (0.2%) |
| Recovered d | |
| No | 1968 (51.9%) |
| Unknown | 1124 (29.7%) |
| Yes | 698 (18.4%) |
| Pregnant | 20 (0.8%) |
| Most frequent post‐vaccination preferred terms e | |
| Thrombosis | 1215 (32.1%) |
| Pulmonary embolism | 777 (20.5%) |
| Deep vein thrombosis | 695 (18.3%) |
| Dyspnoea | 667 (17.6%) |
| Anticoagulant therapy | 646 (17.0%) |
| Headache | 627 (16.5%) |
| Pain in extremity | 623 (16.4%) |
| Cerebrovascular accident | 602 (15.9%) |
| Ultrasound Doppler abnormal | 408 (10.8%) |
| Chest pain | 399 (10.5%) |
| Most frequent pre‐vaccination preferred terms e | |
| No previous medical conditions reported | 1676 (44.2%) |
| Hypertension | 913 (24.1%) |
| Hyperlipidaemia | 349 (9.2%) |
| Obesity | 294 (7.8%) |
| Diabetes mellitus | 272 (7.2%) |
| Gastrooesophageal reflux disease | 251 (6.6%) |
| Depression | 231 (6.1%) |
| Type 2 diabetes mellitus | 223 (5.9%) |
| Asthma | 211 (5.6%) |
| Anxiety | 186 (4.9%) |
For 633 reports, age was missing.
Time to symptom onset, as reported on the VAERS form. For 747 values, onset time was missing.
Serious: events that are reported as resulting in death, life‐threatening adverse experience, hospitalization or prolongation of existing hospitalization, persistent or significant disability/incapacity, or congenital anomaly/birth defect. 11 These designations are defined by the reporter's input. Serious criteria are not mutually exclusive.
Recovery status is defined by the reporter's input (yes, no, unknown) at the time of reporting and may not reflect whether the patient later died or became permanently disabled.
Preferred Terms are not medically confirmed diagnoses, and they are not mutually exclusive.