Table 1.
Associations between BS and risk of glaucoma using Mendelian randomization.
| Exposure | Method | OR | 95% CI | P-value |
|---|---|---|---|---|
| BMI | IVW | 1.20 | 1.02–1.41 | 0.03 |
| BMI | Weighted median | 1.26 | 0.95–1.66 | 0.11 |
| BMI | MR Egger | 1.37 | 0.93–2.02 | 0.12 |
| WHRadjBMI | IVW | 1.09 | 0.88–1.35 | 0.43 |
| WHRadjBMI | Weighted median | 1.01 | 0.74–1.40 | 0.93 |
| WHRadjBMI | MR Egger | 0.87 | 0.26–2.93 | 0.82 |
| WHR | IVW | 1.21 | 0.93–1.57 | 0.14 |
| WHR | Weighted median | 1.27 | 0.87–1.85 | 0.22 |
| WHR | MR Egger | 1.82 | 0.53–6.24 | 0.35 |
| WC | IVW (random effects model) | 1.32 | 1.04–1.69 | 003 |
| WC | Weighted median | 1.32 | 0.95–1.84 | 0.09 |
| WC | MR egger | 1.41 | 0.75–2.67 | 0.29 |
SNP, Single nucleotide polymorphism; BMI, including body mass index; WHRadjBMI, waist-to-hip ratio adjusted by body mass index; WHR, waist-to-hip ratio; WC, waist circumference; IVW, Inverse variance weighted; OR, The effect of the effect allele; CI, Confidence interval; P P-value from the GWAS.