TABLE 2.
Immunopathological features of reported cases
| Case | Histopathology | DIF | IIF | ELISA | Diagnosis |
|---|---|---|---|---|---|
| 1 | Suprabasal intraepithelial cleavage with acantholysis | Intercellular IgG/C3 deposits | Intercellular IgG deposits |
Anti‐DSG1 106 IU/mL (n.v. < 14) Anti‐DSG3 15.5 IU/mL (n.v. < 7) |
PV |
| 2 | Subcorneal acantholysis with neutrophilic infiltration within the blister | Negative | Intercellular IgG deposits | Anti‐DSG1 149 IU/mL (n.v. < 14) | PF |
| 3 | Subcorneal acantholysis with neutrophils within the blister | Intercellular IgG deposits | Negative | Negative | PF |
| 4 | Erosive mucositis with diffuse acantholytic cells | Intercellular IgG/C3 deposits | Intercellular IgG deposits | Anti‐DSG3 70 IU/mL (n.v. < 7) | PV |
| 5 | Intraepithelial cleavage with acantholysis | Intercellular IgG/C3 deposits | Intercellular IgG deposits |
Anti‐DSG1 62.2 IU/mL (n.v. < 14) Anti‐DSG3 157.3 IU/mL (n.v. < 7) |
PV |
Abbreviations: DIF, direct immunofluorescence; DSG1, desmoglein 1; DSG3, desmoglein 3; ELISA, enzyme‐linked immunosorbent assay; IIF, indirect immunofluorescence; n.v. normal value; PF, pemphigus foliaceous; PV, pemphigus vulgaris.