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. 2022 Sep 18;9(8):1144–1148. doi: 10.1002/mdc3.13557

TABLE 1.

Presentation of available case reports

Author Patient Clinical features Symptoms onset day* CSF Lab tests History Brain CT/MRI Treatment
Yüksel et al 9 14 yr F Bilateral shoulder shrugging, choreiform movements in all four limbs and bilateral milkmaid's grip sign 3 NA Iron deficiency anemia Sydenham's chorea Normal Carbamazepine
Sawczyńska et al 5 77 yr F Orofacial dyskinesia and involuntary chorea‐type movements of the trunk and all limbs 11 Normal Elevated serum inflammation markers dyselectrolytemia Arterial hypertension, diabetes mellitus, hypothyroidism, and urinary incontinence and three malignancies in remission Marked features of cerebral small vessel disease. Diffuse white matter hyper intensities, cortical and subcortical atrophy Steroids diazepam remdesivir, IVIG
Cotta Ramusino et al 6 62 yr M Choreiform movements in all four limbs, head, and trunk. Mild encephalopathy (impulsivity, hyperactivity, and attention impairment) Before Mildly decreased glucose mildly increased albumin Normal Type 2 diabetes mellitus and arterial hypertension SWI showed hypointense signal in the dorsolateral portion of both putamina Tetrabenazine, haloperidol
Byrnes et al 7 36 yr M Intermittent rapid, irregular, and no purposeful movements of the both upper extremities with mild encephalopathy Before Mildly elevated lymphocytes Decreased lymphocytes, mildly increased ESR, CRP. Drug abuser Enchantment lesions affecting the bilateral medial putamen and left cerebellum. Solu‐Medrol, IVIG, methylprednisolone
Ghosh et al 8 60 yr M Right‐sided involuntary violent flinging movements in all limbs with semi‐purposeful dancing movement involving both right upper and lower limbs. 2 NA Capillary blood glucose 540, mild neutrophilic leukocytosis, lymphopenia increased ESR CRP, metabolic acidosis, and ketonuria None Left striatal hyperintensity on T1‐weighted imaging Insulin
Revert Barberà et al 11 69 yr F Mixed aphasia, mild right hemiparesis, and choreic movements in all 4 limbs. Headache, focal neurological deficits, seizures, and diffuse encephalopathy. Before NA Elevated d‐dimer levels (3160 μg/L), Fatty liver, fibromyalgia Capsuloganglionic and thalamic infarcts bilaterally, with thrombosis of the lateral veins, left lateral sinus, straight sinus, and vein of Galen
Salari et al 12 13 yr M Large‐amplitude choreic movements affecting the right side of his body that affected his gait 7 after vaccination 0 RBC, 0 WBC, protein 51 (g/L), glucose 56 (mg/dL) Normal None Multiple white matter lesions, one of them enhanced with gadolinium Intravenous methylprednisolone and tetrabenazine
Salari et al 12 18 yr M Choreic movements that mainly affected the left upper limb, shoulder, and the left lower limb. 7 after vaccination 3 RBC, 4 WBC, protein 34 (g/L), glucose 64 (mg/dL) Normal None Few nonspecific white matter lesions Intravenous methylprednisolone and tetrabenazine
This paper case 1 67 yr F Random, fast, irregular, and involuntary choreiform movements in her face and all four limbs, with right arm dominancy. 180 NA Normal None Damaged bilateral basal ganglia Tetrabenazine
This paper case 2 62 yr F Choreiform movements on all limbs, especially on the right side 15 NA Increased ESR, CRP None Normal Tetrabenazine
*

Day of choreiform movement onset since COVID‐19 first symptoms; CSF, cerebrospinal fluid; NA, no data available; IVIG, intravenous infusion of immunoglobulins; CT, computed tomography; MRI, magnetic resonance imaging.