TABLE 1.
Author | Patient | Clinical features | Symptoms onset day* | CSF | Lab tests | History | Brain CT/MRI | Treatment |
---|---|---|---|---|---|---|---|---|
Yüksel et al 9 | 14 yr F | Bilateral shoulder shrugging, choreiform movements in all four limbs and bilateral milkmaid's grip sign | 3 | NA | Iron deficiency anemia | Sydenham's chorea | Normal | Carbamazepine |
Sawczyńska et al 5 | 77 yr F | Orofacial dyskinesia and involuntary chorea‐type movements of the trunk and all limbs | 11 | Normal | Elevated serum inflammation markers dyselectrolytemia | Arterial hypertension, diabetes mellitus, hypothyroidism, and urinary incontinence and three malignancies in remission | Marked features of cerebral small vessel disease. Diffuse white matter hyper intensities, cortical and subcortical atrophy | Steroids diazepam remdesivir, IVIG |
Cotta Ramusino et al 6 | 62 yr M | Choreiform movements in all four limbs, head, and trunk. Mild encephalopathy (impulsivity, hyperactivity, and attention impairment) | Before | Mildly decreased glucose mildly increased albumin | Normal | Type 2 diabetes mellitus and arterial hypertension | SWI showed hypointense signal in the dorsolateral portion of both putamina | Tetrabenazine, haloperidol |
Byrnes et al 7 | 36 yr M | Intermittent rapid, irregular, and no purposeful movements of the both upper extremities with mild encephalopathy | Before | Mildly elevated lymphocytes | Decreased lymphocytes, mildly increased ESR, CRP. | Drug abuser | Enchantment lesions affecting the bilateral medial putamen and left cerebellum. | Solu‐Medrol, IVIG, methylprednisolone |
Ghosh et al 8 | 60 yr M | Right‐sided involuntary violent flinging movements in all limbs with semi‐purposeful dancing movement involving both right upper and lower limbs. | 2 | NA | Capillary blood glucose 540, mild neutrophilic leukocytosis, lymphopenia increased ESR CRP, metabolic acidosis, and ketonuria | None | Left striatal hyperintensity on T1‐weighted imaging | Insulin |
Revert Barberà et al 11 | 69 yr F | Mixed aphasia, mild right hemiparesis, and choreic movements in all 4 limbs. Headache, focal neurological deficits, seizures, and diffuse encephalopathy. | Before | NA | Elevated d‐dimer levels (3160 μg/L), | Fatty liver, fibromyalgia | Capsuloganglionic and thalamic infarcts bilaterally, with thrombosis of the lateral veins, left lateral sinus, straight sinus, and vein of Galen | |
Salari et al 12 | 13 yr M | Large‐amplitude choreic movements affecting the right side of his body that affected his gait | 7 after vaccination | 0 RBC, 0 WBC, protein 51 (g/L), glucose 56 (mg/dL) | Normal | None | Multiple white matter lesions, one of them enhanced with gadolinium | Intravenous methylprednisolone and tetrabenazine |
Salari et al 12 | 18 yr M | Choreic movements that mainly affected the left upper limb, shoulder, and the left lower limb. | 7 after vaccination | 3 RBC, 4 WBC, protein 34 (g/L), glucose 64 (mg/dL) | Normal | None | Few nonspecific white matter lesions | Intravenous methylprednisolone and tetrabenazine |
This paper case 1 | 67 yr F | Random, fast, irregular, and involuntary choreiform movements in her face and all four limbs, with right arm dominancy. | 180 | NA | Normal | None | Damaged bilateral basal ganglia | Tetrabenazine |
This paper case 2 | 62 yr F | Choreiform movements on all limbs, especially on the right side | 15 | NA | Increased ESR, CRP | None | Normal | Tetrabenazine |
Day of choreiform movement onset since COVID‐19 first symptoms; CSF, cerebrospinal fluid; NA, no data available; IVIG, intravenous infusion of immunoglobulins; CT, computed tomography; MRI, magnetic resonance imaging.