TABLE 2.

Organoiridium (III) “half-sandwich” complexes as promising candidates against lung cancer.

No.	IC50 (µM)	Cell lines	Biology and mechanism	References
52	0.62 ± 0.06	A549	Cytotoxicity	Liu et al. (2014)
53	2.1 ± 0.3	A549	Cytotoxicity	Millett et al. (2015)
54	2.09	A549	Cytotoxicity	Mou et al. (2017)
55	1.4 ± 0.2	A549	(1) Arresting cell cycle	Li et al. (2017a)
56	1.1 ± 0.1		(2) Inducing apoptosis
57	5.1 ± 0.3	A549	Cytotoxicity	Li et al. (2018)
58	3.9 ± 0.7	A549	Cytotoxicity	Han et al. (2018)
59	1.99 ± 0.1	A549	Cytotoxicity	Yang et al. (2018)
60	3.6 ± 0.5	A549	Cytotoxicity	He et al. (2018b)
61	2.7 ± 0.1	A549	Cytotoxicity	Kong et al. (2018)
62	14.7 ± 0.4	A549	Cytotoxicity	Zhang et al. (2018)
63	1.01 ± 0.08	A549	Cytotoxicity	Zhang et al. (2020b)
64	1.5 ± 0.3
65	15	A549	Cytotoxicity	Zhang et al. (2020a)
66	4.4 ± 1.2	A549	Cytotoxicity	Liu et al. (2021)
67	1.82 ± 0.06	A549	Cytotoxicity	Chellan et al. (2021)
68	10 ± 1	NCI-H460	Cytotoxicity	Tong et al. (2021)
69	3.79 ± 1.15	A549	Cytotoxicity	Shao et al. (2021)
70	12 ± 3	A549	Cytotoxicity	Komarnicka et al. (2022)