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Immunization schedule of monovalent, sequential, and divalent vaccination strategies. Mice (Balb/c) were immunized at Days 0 and 21 with 7.5 μg of trimer (based on peptidic mass) mixed with equivalent volume (50 μl) of Quick‐Antibody adjuvant. The phosphate‐buffered saline (PBS) mixed with same adjuvant was used as a control group. Detailed groups were shown in Table 1. Two weeks post the second dose (Day 35), all mice were killed and sera were collected for test.
