TABLE 1.
Comparison of laboratory parameters between dead and recovered patients infected with coronavirus disease 2019 (COVID‐19)
| Variables | Dead patients (n = 522) | Recovered patients (n = 556) | p‐Value |
|---|---|---|---|
| Mean age ± SD | 57.8 ± 11.3 | 51.5 ± 12.7 | <.001* |
| Gender (male/female) | 280/242 (53.6/46.4%) | 289/267 (52.0/48.0%) | 0.585 |
| ALT, IU/L (mean ± SD) (reference range: 5–40) | 44.3 ± 23.6 | 33.0 ± 24.5 | <.001* |
| AST, IU/L (mean ± SD) (reference range: 5–40) | 37.0 ± 12.9 | 30.7 ± 15.3 | <.001* |
| ALP, IU/L (mean ± SD) (reference range: up to 306) | 201.1 ± 66.0 | 169.2 ± 89.6 | <.001* |
| Cholesterol, mg/dl (mean ± SD) (reference range: 50–200) | 116.5 ± 38.4 | 123.2 ± 36.9 | <.001* |
| TG, mg/dl (mean ± SD) (Reference range: 60–165) | 117.6 ± 42.2 | 132.2 ± 36.9 | .009* |
| LDL, mg/dl (mean ± SD) (Reference range: up to 150) | 71.4 ± 36.7 | 111.4 ± 48.7 | <.001* |
| HDL, mg/dl (mean ± SD) (Reference range: >40) | 30.5 ± 11.0 | 34.5 ± 11.8 | <.001* |
| WBC, 109/L (mean ± SD) (Reference range: 4000–10,000) | 7600.4 ± 2712.8 | 7738.8 ± 2901.1 | .589 |
| CRP, mg/L (mean ± SD) (reference range: < 10 mg/L negative) | 66.6 ± 21.5 | 56.4 ± 20.8 | <.001* |
| ESR, mm/1st h (mean ± SD) (reference range: 0–15) | 55.1 ± 15.8 | 46.4 ± 15.5 | <.001* |
| FBS, mg/dl (mean ± SD) (reference range: 70–100) | 110.2 ± 42.6 | 106.1 ± 41.5 | .002* |
| Platelets × 1000/cumm (mean ± SD) (reference range: 140,000–400,000) | 185 ± 77 | 184 ± 67 | .317 |
| Haemoglobin, g/dl (mean ± SD) (reference range: 12–18) | 14.4 ± 2.1 | 12.4 ± 1.8 | .363 |
| Uric acid, mg/dl (mean ± SD) (reference range: 3.6–6.8) | 3.4 ± 1.2 | 5.8 ± 1.6 | <.001* |
| Creatinine, mg/dl (mean ± SD) (reference range: 0.6–1.4) | 1.1 ± 0.3 | 0.8 ± 0.3 | <.001* |
| T3, ng/dl (mean ± SD) (reference range: 2.3–4.2) | 3.0 ± 1.1 | 2.6 ± 0.9 | .051 |
| T4, μg/dl (mean ± SD) (reference range: 5.6–13.7) | 9.0 ± 4.7 | 8.4 ± 5.8 | .352 |
| TSH, mu/L (mean ± SD) (reference range: 0.4–4.5) | 3.5 ± 1.8 | 3.3 ± 1.6 | .626 |
| 25‐Hydroxy vitamin D, ng/mL (mean ± SD) (Sufficiency: 21–150) | 27.0 ± 10.2 | 36.2 ± 13.5 | <.001* |
| Real‐time PCR Ct values | 12.5 ± 6.9 | 26.1 ± 8.1 | .021* |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; TG, triglyceride; LDL, low density lipoprotein; HDL, high density lipoprotein; WBC, white blood cells; CRP, C‐reactive protein; ESR, erythrocyte sedimentation rate; FBS, fasting blood glucose; T3, triiodothyronine; T4, thyroxine; TSH, thyroid‐stimulating hormone; Ct, cycle threshold; SD, standard deviation.
*Statistically significant (< 0.05).