TABLE 2.
ACE2 rs2285666 association with COVID‐19 mortality
| Groups | |||||||
|---|---|---|---|---|---|---|---|
| Model | Genotype | Recovered patients | Dead patients | OR (95% CI) | p‐Value | AIC | BIC |
| Allele | C | 810 (73.0%) | 954 (91.0%) | – | – | – | – |
| T | 302 (18.0%) | 90 (0.9%) | – | – | – | – | |
| Codominant | CC | 337 (60.6%) | 443 (84.9%) | 1.00 |
<.0001 |
1402.3 |
1422.3 |
| CT | 136 (24.5%) | 68 (13.0%) | 0.38 (0.28–0.53) | ||||
| TT | 83 (14.9%) | 11 (2.1%) | 0.10 (0.05–0.19) | ||||
| Dominant | CC | 337 (60.6%) | 443 (84.9%) | 1.00 |
<.0001 |
1417.5 |
1432.4 |
| CT‐TT | 219 (39.4%) | 79 (15.5%) | 0.27 (0.20–0.37) | ||||
| Recessive | CC‐CT | 420 (75.5%) | 511 (97.9%) | 1.00 |
<.0001 |
1442.5 |
1452.4 |
| TT | 83 (14.9%) | 11 (2.1%) | 0.12 (0.06–0.23) | ||||
| Overdominant | CC‐TT | 420 (75.5%) | 454 (87.0%) | 1.00 |
<.0001 |
1475.9 |
1490.8 |
| CT | 136 (24.5%) | 68 (13.0%) | 0.46 (0.34–0.64) | ||||
| Minor allele frequency (T) | 0.18 | 0.09 | – | – | – | – | |
Abbreviations: AIC, Akaike information criterion; BIC, Bayesian information criterion; CI, confidence intervals; OR, odds ratios.