Table 1.
Characteristics of 1828 patients infected with Marseille‐4A or Marseille‐4B (a) and risk factor analysis for hospitalization, transfer to the intensive care unit, and death in 1647 patients infected with Marseille‐4A or Marseille‐4B (b).
| a. Characteristics of 1828 patients infected with Marseille‐4A or Marseille‐4B | |||
|---|---|---|---|
| Epidemiological, clinical, and virological features | Marseille‐4A | Marseille‐4B | p Value |
| Male sex (%) | 790 (48.0) | 74 (40.9%) | 0.0710 |
| Mean age in years (standard deviation) | 51.3 (24.1) | 57.5 (21.5) | 0.0008 |
| Mean qPCR C t value (standard deviation) | 20.0 (3.5) | 20.1 (3.8) | 0.9246 |
| Hospitalization (%) | 195 (11.8) | 34 (18.8) | 0.0124 |
| Transfer to intensive care unit (%) | 59 (3.6) | 7 (3.9) | 0.8330 |
| Death (%) | 72 (4.4) | 17 (9.4) | 0.0058 |
| b. Risk factor analysis for hospitalization, transfer to the intensive care unit, and death in 1647 patients infected with Marseille‐4A or Marseille‐4B | |||
|---|---|---|---|
| Epidemiological, clinical, and virological features | OR (95% CI, p value) | ||
| Hospitalization | Transfer to intensive care unit | Death | |
| Male sex | 1.48 (1.08–2.03, p= 0.0142) | 4.70 (2.21–10, p< 0.0001) | 3.07 (1.85–5.1, p< 0.0001) |
| Age | 1.06 (1.05–1.06, p< 0.0001) | 1.03 (1.02–1.05, p< 0.0001) | 1.07 (1.06–1.09, p< 0.0001) |
| qPCR C t value | 1.09 (1.05–1.14, p< 0.0001) | 1.07 (0.98–1.16, p= 0.1368) | 0.97 (0.91–1.04, p= 0.3478) |
| Presence of the stop codon 64 in ORF8 | 2.24 (1.41–3.56, p= 0.0006) | 1.18 (0.41–3.43, p= 0.7625) | 2.60 (1.36–4.98, p= 0.0039) |
Abbreviations: CI, confidence interval; C t, cycle threshold value