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. 2022 Sep 23;13:1002742. doi: 10.3389/fimmu.2022.1002742

Table 3.

The biological function of exosome in the angiogenesis of OS.

EV content Parent cells Target cells Mechanism Biological activity Ref.
synthetic miR-25–3p / OS cells DKK3 Enhance angiogenesis and vascular endothelial cell migration (119)
EWSAT1 / OS cells / Increase in sensitivity/reactivity of vascular endothelial cells (120)
OIP5-AS1 OS cells OS cells miR-153/ATG5 Increase in the angiogenesis level (121)