TABLE 6.
Allergy‐related disorders by helminth exposure
| Helminth exposure | Allergy‐related disorders | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Asthma | Rhinitis | IgE atopy | Food allergy | ||||||
| Yes | No | Yes | No | Yes | No | Yes | No | ||
| High Ascaris IgE | High (≥0.35 kU/L), n (%) | 18 (24.3) | 56 (75.7) | 37 (51.4) | 35 (48.6) | 58 (78.4) | 16 (21.6) | 20 (27.0) | 54 (73.0) |
| Not high (<0.35 kU/L) (Reference group), n (%) | 18 (14.6) | 105 (85.4) | 79 (56.4) | 61 (43.6) | 28 (19.6) | 115 (80.4) | 4 (2.8) | 139 (97.2) | |
| p‐value | .1268 | .560 | <.0001 | <.0001 | |||||
| OR (95% CI) | 1.88 (0.90–3.89) | 0.82 (0.46–1.44) | 14.89 (7.46–29.71) | 12.87 (4.20–39.40) | |||||
| p‐value | .047 | .446 | <.0001 | <.0001 | |||||
| OR (95% CI) | 2.20 (0.66–3.75) | 0.77 (0.40–1.49) | 18.18 (8.02–41.19) | 14.47 (4.17–50.14) | |||||
| Ascaris eggs | Yes, n (%) | 12 (24.5) | 37 (75.5) | 32 (65.3) | 17 (34.7) | 14 (28.6) | 35 (71.4) | 2 (4.1) | 47 (95.9) |
| No (Reference group), n (%) | 23 (15.5) | 125 (84.5) | 78 (52.7) | 70 (47.3) | 63 (41.4) | 89 (58.6) | 20 (13.2) | 132 (86.8) | |
| p‐value | .195 | .138 | .129 | .310 | |||||
| OR (95% CI) | 1.76 (0.80–3.88) | 1.69 (0.86–3.31) | 0.57 (0.28–1.14) | 0.28 (0.06–1.25) | |||||
| p‐value | .048 |
.054 |
.323 | .530 | |||||
| OR (95% CI) | 0.43 (0.24–0.99) | 0.49 (0.24–1.01) | 0.49 (0.24–1.01) | 0.64 (0.16–2.54) | |||||
| Trichuris eggs | Yes, n (%) | 12 (25.0) | 36 (75.0) | 30 (625) | 18 (37.5) | 14 (29.2) | 34 (70.8) | 3 (6.3) | 45 (93.8) |
| No (Reference group), n (%) | 23 (15.4) | 126 (84.6) | 80 (53.7) | 69 (46.3) | 63 (41.2) | 90 (58.8) | 19 (12.4) | 134 (87.6) | |
| p‐value | .135 | .319 | .173 | .297 | |||||
| OR (95% CI) | 1.83 (0.83–4.03) | 1.44 (0.74–2.80) | 0.59 (0.29–1.19) | 0.47 (0.13–1.66) | |||||
| p‐value | .024 | .500 | .563 | .666 | |||||
| OR (95% CI) | 0.36 (0.15–0.87) | 0.79 (0.39–1.58) | 0.80 (0.37–1.71) | 0.74 (0.19–2.92) | |||||
Subtotals are not always equal due to some missing data.
Abbreviations: aOR, adjusted odds ratio (adjusted for age, gender and locality); IgE, immunoglobulin E.