Table 3.
Subgroup analysis for CVD, cancer and all-cause mortality according to the groups of bone mineral density (mg/cm2).
| All-cause mortality | Osteoporosis | Osteopenia | Normal | P-trend | P-interaction | |
|---|---|---|---|---|---|---|
| Age | age<50 years | 2.62 (0.25,27.64) | 1.40 (0.99,1.98) | 1 | 0.0382 | 0.0017 |
| age≥50 years | 2.80 (2.29,3.42) | 1.43 (1.20,1.71) | 1 | < 0.0001 | ||
| Gender | male | 1.00 (0.09,11.25) | 1.00 (0.82,1.22) | 1 | 1 | 0.4129 |
| female | 1.35 (1.03,1.77) | 1.08 (0.84,1.39) | 1 | 0.0257 | ||
| Race | non-Hispanic white | 1.42 (1.09,1.85) | 1.05 (0.86,1.21) | 1 | 0.0547 | 0.1302 |
| non-Hispanic black | 1.34 (0.91,1.98) | 1.05 (0.86,1.27) | 1 | 0.3182 | ||
| mexican American | 1.32 (0.85,2.05) | 1.25 (1.00,1.57) | 1 | 0.0353 | ||
| other | 0.73 (0.25,2.15) | 0.92 (0.45,1.89) | 1 | 0.6313 | ||
| BMI | BMI<25 kg/m2 | 1.49 (1.08,2.07) | 1.11 (0.81,1.53) | 1 | 0.0149 | 0.0025 |
| BMI≥25 kg/m2 | 1.20 (0.85,1.69) | 1.00 (0.84,1.20) | 1 | 0.5817 | ||
| CVD mortality | ||||||
| Age | age<50 years | 0 | 1.40 (0.99,1.98) | 1 | 0.6875 | 0.0821 |
| age≥50 years | 2.30 (1.57,3.35) | 1.27 (0.96,1.67) | 1 | 0.0008 | ||
| Gender | male | 1.30 (0.62,2.70) | 0.80 (0.58,1.10) | 1 | 0.3943 | 0.1679 |
| female | 0.99 (0.63,1.56) | 0.94 (0.67,1.30) | 1 | 0.9804 | ||
| Race | non-Hispanic white | 0.95 (0.61,1.49) | 0.80 (0.61,1.06) | 1 | 0.5065 | 0.4231 |
| non-Hispanic black | 1.07 (0.53,2.17) | 1.30 (0.88,1.93) | 1 | 0.2871 | ||
| mexican American | 2.17 (0.83,5.65) | 1.40 (0.97,2.04) | 1 | 0.0483 | ||
| other | 0.28 (0.02,3.87) | 0.20 (0.07,0.56) | 1 | 0.0162 | ||
| BMI | BMI<25 kg/m2 | 1.38 (0.42,4.50) | 0.62 (0.15,2.53) | 1 | 0.4649 | 0.1292 |
| BMI≥25 kg/m2 | 1.01 (0.55,1.86) | 0.89 (0.67,1.19) | 1 | 0.6727 | ||
| Cancer mortality | ||||||
| Age | age<50 years | 0 | 2.34 (1.42,3.86) | 1 | 0.0015 | 0.075 |
| age≥50 years | 1.33 (0.75,2.34) | 1.25 (0.91,1.72) | 1 | 0.1403 | ||
| Gender | male | 0.53 (0.12,2.41) | 1.25 (0.82,1.91) | 1 | 0.5357 | 0.1122 |
| female | 1.18 (0.57,2.45) | 1.29 (0.79,2.09) | 1 | 0.5054 | ||
| Race | non-Hispanic white | 1.04 (0.52,2.07) | 1.31 (0.89,1.93) | 1 | 0.4634 | 0.421 |
| non-Hispanic black | 0.51 (0.11,2.35) | 0.85 (0.58,1.24) | 1 | 0.1775 | ||
| mexican American | 0.13 (0.02,0.75) | 1.57 (0.70,3.53) | 1 | 0.7119 | ||
| other | 0.20 (0.02,2.00) | 1.21 (0.31,4.68) | 1 | 0.6598 | ||
| BMI | BMI<25 kg/m2 | 1.46 (0.60,3.59) | 1.98 (1.07,3.69) | 1 | 0.1818 | 0.3094 |
| BMI≥25kg/m2 | 0.64 (0.25,1.64) | 0.98 (0.65,1.46) | 1 | 0.6401 | ||
| Cerebral mortality | ||||||
| Age | age<50 years | 0 | 0.85 (0.13,5.71) | 1 | 0.8442 | 0.1441 |
| age≥50 years | 2.75 (0.97,7.78) | 1.54 (0.78,3.04) | 1 | 0.0657 | ||
| Gender | male | 2.99 (0.53,16.80) | 099 (0.39,2.48) | 1 | 0.6714 | 0.9782 |
| female | 0.66 (0.19,2.24) | 0.81 (0.36,1.82) | 1 | 0.4954 | ||
| Race | non-Hispanic white | 1.00 (0.28,3.56) | 0.99 (0.42,2.39) | 1 | 0.9996 | 0.0374 |
| non-Hispanic black | 0.74 (0.14,3.87) | 1.28 (0.65,2.51) | 1 | 0.7815 | ||
| mexican American | 0.33 (0.05,2.02) | 0.73 (0.30,1.81) | 1 | 0.3020 | ||
| other | 0 | 2.43 (0.04,146.33) | 1 | < 0.0001 | ||
| BMI | BMI<25 kg/m2 | 2.49 (0.06,99.42) | 0.50 (0.02,15.92) | 1 | 0.3836 | 0.5789 |
| BMI≥25kg/m2 | 1.39 (0.45,4.30) | 1.16 (0.57,2.37) | 1 | 0.575 | ||
| Heart disease mortality | ||||||
| Age | age<50 | 0 | 0.87 (0.33,2.33) | 1 | 0.7651 | 0.18 |
| age≥50 | 2.22 (1.38,3.55) | 1.21 (0.90,1.63) | 1 | 0.0099 | ||
| Gender | male | 1.10 (0.52,2.36) | 0.77 (0.55,1.08) | 1 | 0.2501 | 0.1169 |
| female | 1.16 (0.64,2.12) | 0.99 (0.66,1.49) | 1 | 0.5961 | ||
| Race | non-Hispanic white | 0.97 (0.59,1.62) | 0.79 (0.58,1.62) | 1 | 0.4832 | 0.701 |
| non-Hispanic black | 1.20 (0.43,3.34) | 1.32 (0.79,2.20) | 1 | 0.3673 | ||
| mexican American | 4.03 (1.47,11.04) | 1.85 (1.25,2.74) | 1 | 0.0017 | ||
| other | 0.72 (0.07,7.06) | 0.39 (0.14,1.14) | 1 | 0.3418 | ||
| BMI | BMI<25 kg/m2 | 0.84 (0.40,1.75) | 0.72 (0.37,1.40) | 1 | 0.6573 | 0.0826 |
| BMI≥25 kg/m2 | 0.95 (0.47,1.91) | 0.84 (0.62,1.14) | 1 | 0.473 | ||
Adjusted for variables in model 4.