Figure 1.
Association of sarcopenia with overall survival. Representative (A) sagittal and transversal computed tomography (CT) images at the inferior aspect of the third lumbar vertebra. Red markings indicate the cross-sectional area of both psoas muscles and areas encircled in white indicate subcutaneous fat. (B) Psoas muscle index (PMI) stratified by gender (n = 92). P value calculated using the Mann-Whitney U test. (C) Patient ECOG score in relation to PMI (n = 92). P value calculated using the Kruskal-Wallis test. (D) Kaplan-Meier curve depicting survival analysis based on sarcopenia. (E) Intramuscular adipose content (IMAC) stratified by gender (n = 90). Two patients were excluded from analysis due to almost complete absence of subcutaneous fat tissue on abdominal imaging. Dotted line represents the threshold between normal and increased intramuscular adipose content based on sex-specific 25th percentile. P value calculated using the Mann-Whitney U test. (F) Kaplan-Meier curve depicting survival analysis based on IMAC. P values in (D, F) were calculated with the log-rank test. Each tick mark on the Kaplan-Meier curve represents a censored event. Each data point in (B, C, E) represents an individual patient. Red dots in (B, C) indicate sarcopenic patients with a PMI value below the sex-specific 25th percentile and cut offs were 6.03 cm2/m2 for males and 5.11 cm2/m2 for females. Red lines represent the median of the dataset.