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. 2022 Sep 23;12:1007918. doi: 10.3389/fonc.2022.1007918

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Copyright © 2022 Cui, Liu, Wang, Gu, Wang, Sun and Wei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune microenvironment analysis and gene set enrichment analysis (GSEA). (A) Allograft rejection, asthma, autoimmune thyroid disease, cell adhesion molecules CAMs, and systemic lupus erythematosus are among the enriched KEGG pathways in the high-risk group. (B) Aminoacyl tRNA biosynthesis, dna replication, nucleotide excision repair, O-glycan biosynthesis, and oocyte meiosis are among the enriched KEGG pathways in the low-risk group. (C–E) The high-risk and low-risk groups had considerably different Stromal, ESTIMATE, and Immune scores, with the high-risk group having higher scores. (F–H) A Pearson correlation analysis revealed a strong positive relation between Stromal score, ESTIMATE score, Immune score and risk score.