Table 3.

Benign/Likely benign variants.

Gene	Patient	Chromosomal position*		AA change	Nucleotide change	Exon	Type	Zygosity	dbSNP ID	AF (EgyptRef)	Global AF
CFH	PI17	196643015		p.T91=	c.273T>C	Exon 3	Synonymous	Het	–	–	–
CFH	LN16	196646739		p.D187=	c.561T>C	Exon 5	Synonymous	Het	–	–	–
CFH	LN3	196654300		p.Y299=	c.897T>C	Exon 7	Synonymous	Het	–	–	–
CFH	LN14	196684820		p.G539=	c.1617T>C	Exon 12	Synonymous	Het	rs147170171	–	0.0000598
CFH	PI19	196684844		p.T547=	c.1641C>T	Exon 12	Synonymous	Het	–	–	–
CFH	LN3	196684855		p.I551T	c.1652T>C	Exon 12	Missense	Het	rs35453854	0.009091	0.00396
CFH	PI18	196684859		p.V552=	c.1656G>A	Exon 12	Synonymous	Hom	–	–	–
CFH	PI20	196697588		p.G783=	c.2349A>T	Exon 16	Synonymous	Het	–	–	–
CFH	PI11	196712655		p.S1096=	c.3207T>C	Exon 21	Synonymous	Het	rs62641697	–	0.00104
CD46	PI21	207925593		p.P12=	c.36T>C	Exon 1	Synonymous	Het	–	–	–
CD46	LN 18	207925626		p.A23=	c.69C>T	Exon 1	Synonymous	Het	–	–	–

PI, post-infectious; LN, lupus nephritis; Het, heterozygous; Hom, homozygous; AF, Global (gnomAD: Exomes).

*Chromosomal positions are according to GRCh37.