Table 2.
Estimation | 95% CI lower | 95% CI upper | p-value | |
---|---|---|---|---|
TC ACME ADE Total effect Prop.Mediated HDL |
−0.00031 0.058 0.058 −0.0046 |
−0.0010 0.050 0.049 −0.017 |
0.00 0.070 0.070 0.00 |
0.13 p<2 × 10−16 2 × 10−16 0.13 |
ACME | 0.0059 | 0.0029 | 0.010 | <2 × 10−16 |
ADE | 0.052 | 0.045 | 0.060 | <2 × 10−16 |
Total effect | 0.058 | 0.051 | 0.060 | <2 × 10−16 |
Prop.Mediated | 0.102 | 0.049 | 0.15 | <2 × 10−16 |
LDL | ||||
ACME ADE Total effect Prop.Mediated |
0.00013 0.058 0.058 0.0020 |
−0.00020 0.051 0.051 −0.0034 |
0.000 0.060 0.070 0.010 |
0.44 <2 × 10−16 <2 × 10−16 0.44 |
TG ACME ADE Total effect Prop.Mediated |
0.0052 0.053 0.058 0.089 |
0.0035 0.046 0.051 0.058 |
0.010 0.060 0.060 0.12 |
<2 × 10−16 <2 × 10−16 <2 × 10−16 <2 × 10−16 |
ACME, average causal mediation effect; ADE, average direct effect.