Table 4.

The effect of BMI on serum urate and lipid traits.

Outcome	Method	nSNPs	Betas (95% CI)	p-value
Urate	IVW	851	0.30 (0.25, 0.34)	2.37 × 10−35
	MR-Egger	851	0.34 (0.21, 0.48)	6.06 × 10−7
	Egger-intercept		−0.00076	0.45
	WME	851	0.31 (0.25, 0.36)	1.37 × 10−32
	MR-PRESSO	838	0.32 (0.29, 0.35)	6.71 × 10−65
TC	IVW	856	−0.030 (−0.075, 0.015)	0.18
	MR-Egger	856	−0.16 (−0.28, −0.042)	0.0071
	Egger-intercept		0.0022	0.018
	WME	856	−0.039 (−0.078, 0.00020)	0.054
	MR-PRESSO	820	−0.029 (−0.070, 0.012)	0.17
HDL	IVW	964	−0.30 (−0.32, −0.27)	1.39 × 10−104
	MR-Egger	964	−0.31 (−0.38, −0.23)	3.93 × 10−14
	Egger-intercept		0.00014	0.81
	WME	964	−0.29 (−0.31, −0.28)	5.18 × 10−197
	MR-PRESSO	863	−0.32 (−0.32, −0.30)	1.69 × 10−203
LDL	IVW	964	−0.068 (−0.10, −0.034)	9.45 × 10−5
	MR-Egger	964	−0.20 (−0.30, −0.098)	1.04 × 10−4
	Egger-intercept		0.0020	0.0066
	WME	964	−0.060 (−0.079, −0.042)	5.24 × 10−10
	MR-PRESSO	908	−0.049 (−0.054, −0.035)	4.40 × 10−12
TG	IVW	964	0.21 (0.18, 0.25)	1.15 × 10−39
	MR-Egger	964	0.18 (0.091, 0.28)	1.11 × 10−4
	Egger-intercept		0.00047	0.50
	WME	964	0.23 (0.21, 0.245)	5.62 × 10−105
	MR-PRESSO	853	0.25 (0.23, 0.27)	4.36 × 10−142