Table 5.
Exposure | Method | nSNPs | Betas (95% CI) | p-value |
---|---|---|---|---|
TC | IVW | 109 | −0.035 (−0.096, 0.026) | 0.26 |
MR-Egger | 109 | 0.019 (−0.10, 0.14) | 0.75 | |
Egger-intercept | −0.0029 | 0.31 | ||
WME | 109 | −0.048 (−0.097, 0.001) | 0.055 | |
MR-PRESSO | 101 | −0.020 (−0.077, 0.037) | 0.49 | |
HDL | IVW | 208 | −0.090 (−0.14, −0.039) | 0.00047 |
MR-Egger | 208 | −0.00056 (−0.074, 0.072) | 0.99 | |
Egger-intercept | −0.0032 | 0.0013 | ||
WME | 208 | −0.059 (−0.12, 0.00069) | 0.054 | |
MR-PRESSO | 203 | −0.080 (−0.13, −0.035) | 0.00057 | |
LDL | IVW | 79 | −0.0027 (−0.13, 0.12) | 0.97 |
MR-Egger | 79 | 0.071 (−0.16, 0.30) | 0.55 | |
Egger-intercept | −0.024 | 0.46 | ||
WME | 79 | −0.043 (−0.14, 0.057) | 0.39 | |
MR-PRESSO | 74 | −0.065 (−0.14, 0.0075) | 0.084 | |
TG | IVW | 174 | 0.22 (0.15, 0.29) | 2.28 × 10−10 |
MR-Egger | 174 | 0.11 (0.0024, 0.22) | 4.66 × 10−2 | |
Egger-intercept | 0.0033 | 0.013 | ||
WME | 174 | 0.15 (0.077, 0.23) | 1.73 × 10−4 | |
MR-PRESSO | 164 | 0.19 (0.14, 0.24) | 1.84 × 10−10 |