Table 2.
Information of the top 15 drugs filtered by Interaction score.
| Gene | Drug | Interaction_types | Interaction score | PubMed ID |
|---|---|---|---|---|
| SOST | ROMOSOZUMAB | inhibitor | 63.65 | 28755782 |
| PTGFR | TRAVOPROST | agonist | 48.67 | 19929706|18983226 |
| PTGFR | LATANOPROST | agonist | 19.97 | 15037111|9733584 |
| PTGFR | TAFLUPROST | agonist | 14.98 | 21858491 |
| PTGFR | BIMATOPROST | agonist | 14.98 | 14733708|17724194 |
| SLC6A2 | REBOXETINE | inhibitor | 9.09 | 12388649 |
| SLC6A2 | DEXMETHYLPHENIDATE | inhibitor | 7.14 | 11160413|18480678 |
| SLC6A2 | GUANETHIDINE | inducer | 6.5 | 16126010|8710929 |
| CA3 | ACETAZOLAMIDE | inhibitor | 4.9 | 20605094|1909176 |
| SLC6A2 | ATOMOXETINE | inhibitor | 4.42 | 14709944|16142049 |
| SLC6A2 | PHENMETRAZINE | inhibitor | 3.9 | 12106802|17139284 |
| PTGFR | DINOPROST TROMETHAMINE | agonist | 3.74 | 8777582 |
| CA3 | ETHOXZOLAMIDE | inhibitor | 3.26 | 17826101 |
| SLC6A2 | DIETHYLPROPION | inhibitor | 3.25 | 19897080|17139284 |
| SLC6A2 | SIBUTRAMINE | inhibitor | 3.03 | 16678551|19475780 |