Figure 2.

Suppression of UV‐induced CPD by NPS‐2143 in human keratinocytes. (a) CPD in vitro by immunohistochemistry and image analysis at 3 h post UV with treatments as indicated. Media contained 1.0 mm Ca²⁺ _o. Data were shown as mean + SEM (n = 9). ****P < 0.0001, ***P < 0.001, n.s. not significant, when compared with UV+vehicle. n.s. (with bar) not significantly different from one another. ####, P < 0.0001 significantly different from UV+vehicle b) Photomicrographs of CPD in vitro b). Black arrows point to the dark brown staining in nuclei indicating the presence of CPD. Scale bar = 100 µm