TABLE 2.
Annual change in single SARA item scores and aggregated subscores in male and female SCA3 patients
Sex | |||||
---|---|---|---|---|---|
Male (n = 80) | Female (n = 76) | Difference | |||
Mean ± SD | % of total | Mean ± SD | % of total | P value | |
Single items | |||||
Gait | 0.30 ± 0.85 | 14.9 | 0.17 ± 0.90 | 17.7 | 0.36 |
Stance | 0.35 ± 0.87 | 17.3 | 0.18 ± 1.20 | 18.8 | 0.32 |
Sitting | 0.31 ± 0.76 | 15.3 | 0.22 ± 0.70 | 22.9 | 0.45 |
Speech | 0.19 ± 0.77 | 9.4 | 0.21 ± 0.68 | 21.9 | 0.84 |
Finger chase | 0.11 ± 0.65 | 5.4 | 0.11 ± 0.55 | 11.5 | 0.99 |
Nose‐finger test | 0.04 ± 0.63 | 2.0 | −0.08 ± 0.66 | −8.3 | 0.24 |
Diadochokinesia | 0.34 ± 0.73 | 16.8 | 0.08 ± 0.77 | 8.3 | 0.033 |
Heel‐shin slide | 0.38 ± 0.71 | 18.8 | 0.07 ± 0.78 | 7.3 | 0.009 |
Aggregated subscores | |||||
Axial | 0.96 ± 1.62 | 47.5 | 0.58 ± 1.97 | 60.4 | 0.19 |
Upper limb | 0.49 ± 1.38 | 24.3 | 0.11 ± 1.22 | 11.5 | 0.069 |
Appendicular | 0.87 ± 1.69 | 43.1 | 0.17 ± 1.53 | 17.7 | 0.008 |
Total | 2.02 ± 2.78 | 100 | 0.96 ± 2.85 | 100 | 0.02 |