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Potential mechanisms involved in ketamine's anxiolytic and antidepressant effects. AMPA, α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid; BDNF, brain‐derived neurotropic factor; CYP2B6, cytochrome P450 2B6; CYP2A6, cytochrome P450 2A6; 4E‐BPs, eukaryotic initiation factor 4E‐binding proteins; GABA, γ‐aminobutyric acid; (2R,6R)‐HNK, (2R,6R)‐hydroxynorketamine; mTORC1, mammalian target of rapamycin complex‐1; NMDA, N‐methyl‐d‐aspartate. The figure was created with BioRender.com
