Skip to main content
. 2022 Sep 2;600(18):4187–4205. doi: 10.1113/JP283021

Figure 9. The effects of opioid receptor agonists on oIPSCs recorded from female and male rats were similar.

Figure 9

A and B, graphs showing the effect of μ‐, κ‐ and δ‐opioid agonists (DAMGO, U69593 and deltorphin II respectively) on the oIPSC peak amplitude (A) and PPR (B) in tissue from female (F, closed circles) and male (M, open circles) rats (μ: 20 cells (F), 18 cells (M); κ: 17 cells (F), 24 cells (M); δ: 10 cells (F), 10 cells (M), two‐tailed unpaired t test). C, changes in holding current of non‐DF neurons induced by DAMGO (Mann‐Whitney test) and (D) the proportion of neurons did not show significant differences between in male and female rats (Fisher's exact test). Values on top of the bars indicate the number of responding non‐DF neurons and those below the bars indicate the total number of cells treated. Bars in A–C indicate means ± SD. [Colour figure can be viewed at wileyonlinelibrary.com]