Figure 2.

Urinary excretion of fexofenadine after oral administration of fexofenadine (60 mg) with 150 mL of an aqueous solution of (−)‐epigallocatechin gallate (EGCG)‐concentrated green tea extract (○), or water (●) in 10 healthy volunteers. (a) Cumulative urinary excretion (mg) of fexofenadine over 24 hours after administration, (b) % of dose, and (c) renal clearance (CL_R) of fexofenadine. Data are expressed as the arithmetic mean ± SD. **, P < 0.01 with respect to water phase. GTE, green tea extract.