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. 2022 May 29;112(2):327–334. doi: 10.1002/cpt.2622

Table 2.

Model‐predicted clinical response rates following treatment with mobocertinib 160 mg q.d. and 120 mg q.d.

Outcome Predictor Predicted response rate, % (95% CI) Odds ratio (95% CI) P value
160 mg q.d. 120 mg q.d.
Longitudinal clinical response (PR or better) Normalized dynamic molar sum exposure 30.7 (23.2, 39.4) 27.9 (21.3, 35.8) 0.78 (0.55, 1.10) 0.156
Best confirmed response (PR or better) Time‐averaged molar sum exposure 26.7 (19.3, 35.6) 24.5 (16.9, 34.1) 0.89 (0.71, 1.12) 0.316

CI, confidence interval; PR, partial response.