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. 2022 Sep 23;13:933241. doi: 10.3389/fimmu.2022.933241
KIRC kidney renal clear cell carcinoma
TME tumor microenvironment
ICB immune checkpoint inhibitors
OS overall survival
RCC renal cell carcinoma
ROS reactive oxygen species
CTR-1 copper transporter 1
PD-1 programmed cell death 1
PD-L1 programmed cell death 1 ligand 1
CTLA-4 cytotoxic T lymphocyte-associated antigen-4
MAGE-A3 Melanoma antigen family A-3
TCGA The Cancer Genome Atlas
DEGs differentially expressed genes
FC fold change
GSEA gene set enrichment analysis
NES normalized enrichment score
GO Gene Ontology
KEGG Kyoto Encyclopedia of Genes and Genomes
TIP Tracking Tumor Immunophenotype
ssGSEA single-sample gene set enrichment analysis
TIS T cell inflamed score
LASSO least absolute shrinkage and selection operator
K–M Kaplan–Meier
ROC receiver operating characteristic
AUC area under curve
TILs tumor infiltrating leukocytes
MCP microenvironment cell populations
Quantiseq quantification of the tumor immune contexture from human RNA-seq data
TIMER tumor immune estimation resource
NK cell nature killer
Th1 cell type 1 T helper cell
scRNA-seq single-cell RNA sequencing
VSM vascular smooth muscle
m6A N6-methyladenosine
TNF tumor necrosis factor
RSF random survival forest