KIRC | kidney renal clear cell carcinoma |
TME | tumor microenvironment |
ICB | immune checkpoint inhibitors |
OS | overall survival |
RCC | renal cell carcinoma |
ROS | reactive oxygen species |
CTR-1 | copper transporter 1 |
PD-1 | programmed cell death 1 |
PD-L1 | programmed cell death 1 ligand 1 |
CTLA-4 | cytotoxic T lymphocyte-associated antigen-4 |
MAGE-A3 | Melanoma antigen family A-3 |
TCGA | The Cancer Genome Atlas |
DEGs | differentially expressed genes |
FC | fold change |
GSEA | gene set enrichment analysis |
NES | normalized enrichment score |
GO | Gene Ontology |
KEGG | Kyoto Encyclopedia of Genes and Genomes |
TIP | Tracking Tumor Immunophenotype |
ssGSEA | single-sample gene set enrichment analysis |
TIS | T cell inflamed score |
LASSO | least absolute shrinkage and selection operator |
K–M | Kaplan–Meier |
ROC | receiver operating characteristic |
AUC | area under curve |
TILs | tumor infiltrating leukocytes |
MCP | microenvironment cell populations |
Quantiseq | quantification of the tumor immune contexture from human RNA-seq data |
TIMER | tumor immune estimation resource |
NK cell | nature killer |
Th1 cell | type 1 T helper cell |
scRNA-seq | single-cell RNA sequencing |
VSM | vascular smooth muscle |
m6A | N6-methyladenosine |
TNF | tumor necrosis factor |
RSF | random survival forest |