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. 2022 Sep 20;10:1018399. doi: 10.3389/fpubh.2022.1018399

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Copyright © 2022 Selvavinayagam, Yong, Joseph, Hemashree, Tan, Zhang, Rajeshkumar, Kumaresan, Kalpana, Kalaivani, Monika, Suvaithenamudhan, Kannan, Murugesan, Narayanasamy, Palani, Larsson, Shankar and Raju.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Comparison of spike protein mutations of the Omicron BA.11.529, BA.1.1, BA.2, and Delta B.1.617.2 lineages. The color indicates the prevalence of S protein mutations from available sequences from GISAID Initiative as of 20th July 2022. (B) SARS-CoV-2 spike monomer genome arrangement. N-terminal domain (NTD), receptor binding domain (RBD), fusion peptide (FP), heptad repeat (HR1 and 2), trans-membrane region (TM), intracellular domain (ICD).