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. 2022 Sep 20;10:1018399. doi: 10.3389/fpubh.2022.1018399

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Copyright © 2022 Selvavinayagam, Yong, Joseph, Hemashree, Tan, Zhang, Rajeshkumar, Kumaresan, Kalpana, Kalaivani, Monika, Suvaithenamudhan, Kannan, Murugesan, Narayanasamy, Palani, Larsson, Shankar and Raju.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Factors associated with disease severity. (A) Univariate binary regression analysis of factors associated with disease severity, use of medical supports and disease prognosis. (B) A circular view of the phylogenetic tree representing the origin of omicron variants. The variants and their disease severity are grouped and classified in their respective colors. Sig. assoc., significant association; ICU, intensive care unit; CKD, chronic kidney disease; CLD, chronic liver disease. *, **, ***, **** represent P < 0.05, <0.01, <0.001 and <0.0001, respectively.