Table 2.

Multi-variate analysis of factors associated with disease severity, medical support required and treatment outcomes.

Outcome	Variable	Coeff. (95% CI)	P-value
Asymptomatic and mild disease	SARS-CoV-2 VL	1.05 (0.89, 1.25)	0.563
	No. of vaccine doses	0.69 (0.53, 0.89)	0.004**
	No. of comorbidities	1.06 (0.85, 1.32)	0.594
	Omicron BA.2	0.64 (0.35, 1.19)	0.163
Severe disease	SARS-CoV-2 VL	1.28 (1.08, 1.63)	0.043*
	No. of vaccine doses	0.82 (0.58, 1.16)	0.259
	No. of comorbidities	0.97 (0.73, 1.29)	0.827
	Omicron BA.2	0.34 (0.17, 0.68)	0.002**
Oxygen support	SARS-CoV-2 VL	1.25 (1.04, 1.49)	0.015*
	No. of vaccine doses	1.03 (0.79, 1.34)	0.856
	No. of comorbidities	0.61 (0.48, 0.77)	<0.0001****
	Omicron BA.2	3.05 (1.57, 5.93)	0.001***
HDU/ICU	SARS-CoV-2 VL	1.25 (1.05, 1.49)	0.014*
	No. of vaccine doses	1.07 (0.82, 1.39)	0.639
	No. of comorbidities	0.6 (0.47, 0.76)	<0.0001****
	Omicron BA.2	2.87 (1.49, 5.52)	0.002**
Ventilator	SARS-CoV-2 VL	1.26 (0.89, 1.50)	0.255
	No. of vaccine doses	1.17 (0.80, 1.72)	0.410
	No. of comorbidities	0.71 (0.52, 1.01)	0.054†
	Omicron BA.2	3.35 (0.98, 11.5)	0.054†
Recovery	SARS-CoV-2 VL	0.93 (0.75, 1.16)	0.534
	No. of vaccine doses	1.35 (0.97, 1.88)	0.052†
	1 dose	1.00 (ref)	–
	2 doses	1.83 (0.94, 3.56)	0.054†
Death	SARS-CoV-2 VL	1.07 (0.86, 1.33)	0.534
	No. of vaccine doses	0.74 (0.53, 1.03)	0.052†
	No. of comorbidities	1.47 (1.09, 1.98)	0.012*
	Omicron BA.2	3.6 (1.14, 8.18)	0.026*

All data reported as median of coefficients, 95% confident intervals; p-values. ^**, ^***, ^**** represent P < 0.05, <0.01, <0.001 and <0.0001, respectively.

^†Having a trend of association, but not statistically significant. VL, viral load (nasopharyngeal).