Table 3.

Association of SNPs in TRAPPC9 and CD4 genes on SCC, SCS, milk production, and serum cytokines traits in Chinese Holsteins.

SNP	Genotype	Fat (%)	Protein (%)	IL-6	IFN-γ	SCC	SCS
SNP1	CC(303)	4.09 ± 0.05	2.93 ± 0.15	67.19 ± 1.43	96.43 ± 1.12	330.98 ± 39.93	2.60 ± 0.15
(TRAPPC9)	CT(3)	4.43 ± 0.53	3.82 ± 0.18	57.58 ± 16.83	107.23 ± 13.22	40.66 ± 400.05	1.69 ± 1.46
	TC(5)	4.44 ± 0.41	2.91 ± 0.15	77.18 ± 11.90	100.71 ± 9.35	162.2 ± 309.87	2.80 ± 1.13
	P-value	0.57	< 0.0001***	0.59	0.65	0.67	0.81
SNP2	AA(122)	4.08 ± 0.08	3.05 ± 0.03	70.03 ± 2.23	95.28 ± 1.75	219.87 ± 62.23	2.08 ± 0.23
(TRAPPC9)	AG(144)	4.12 ± 0.07	3.06 ± 0.02	65.62 ± 2.08	98.65 ± 1.64	375.36 ± 57.68	2.87 ± 0.21
	GG (46)	4.08 ± 0.13	3.04 ± 0.05	64.70 ± 2.66	94.21 ± 2.88	444.8 ± 101.34	3.05 ± 0.37
	P-value	0.89	0.87	0.26	0.24	0.08	0.01**
SNP3	TT(64)	4.16 ± 0.12	3.04 ± 0.04	65.08 ± 3.09	96.78 ± 2.44	515.68 ± 85.52	2.91 ± 0.31
(TRAPPC9)	TG(158)	4.14 ± 0.07	3.08 ± 0.03	64.85 ± 1.96	97.88 ± 1.55	316.07 ± 54.50	2.83 ± 0.20
	GG(90)	4.99 ± 0.10	3.03 ± 0.04	72.96 ± 2.59	94.43 ± 2.05	201.79 ± 74.52	1.92 ± 0.26
	P-value	0.41	0.48	0.03**	0.41	0.02**	0.01**
SNP4	CC(148)	4.07 ± 0.08	3.07 ± 0.03	63.14 ± 2.01	98.33 ± 1.59	294.85 ± 56.97	2.79 ± 0.21
(CD4)	CT(141)	4.12 ± 0.08	3.03 ± 0.03	68.64 ± 2.02	96.53 ± 1.62	376.8 ± 58.98	2.51 ± 0.21
	TT(23)	4.19 ± 0.19	3.15 ± 0.02	85.32 ± 5.17	86.18 ± 4.14	195.26 ± 144.03	1.75 ± 0.52
	P-value	0.82	0.23	0.0003***	0.02**	0.39	0.17

P-value is the significance level from analyses of the association of SNPs with milk production, SCC, SCS, and serum cytokines traits in Chinese Holsteins

(^***P < 0.001;

^**P < 0.01;

^*P < 0.05).