Table 4.

Genetic effect of SNPs in TRAPPC9 and CD4 genes on milk production, mastitis resistance and serum cytokine traits in Chinese Holstein.

SNPs	Effect	Fat %	Protein %	IL-6	IFN-γ	SCC	SCS
SNP1	A	−0.18 ± 0.21	0.07 ± 0.07	−4.99 ± 5.99	−2.14 ± 4.71	84.39 ± 156.21	−0.09 ± 0.57
	P-value	0.39	0.35	0.41	0.64	0.58	0.86
	D	0.16 ± 0.56	1.15 ± 0.20	−14.61 ± 17.87	8.67 ± 14.03	−205.92 ± 429.46	−1.009 ± 1.57
	P-value	0.78	<0.0001***	0.41	0.53	0.68	0.52
SNP2	A	0.00 ± 0.08	0.003 ± 0.03	2.66 ± 2.14	0.54 ± 1.69	−112.45 ± 59.45	−0.48 ± 0.22
	P-value	0.99	0.91	0.21	0.75	0.06	0.02**
	D	0.04 ± 0.11	0.02 ± 0.04	−1.74 ± 2.99	3.91 ± 2.35	46.83 ± 82.83	0.30 ± 0.30
	P-value	0.66	0.61	0.56	0.99	0.61	0.32
SNP3	A	0.08 ± 0.08	0.01 ± 0.03	−3.94 ± 2.01	1.17 ± 1.59	156.95 ± 56.06	0.50 ± 0.20
	P-value	0.26	0.86	0.05 *	0.46	0.005 ***	0.02 **
	D	0.07 ± 0.10	0.05 ± 0.04	−4.17 ± 2.81	2.29 ± 2.22	−42.66 ± 78.26	0.42 ± 0.29
	P-value	0.53	0.25	0.13	0.31	0.58	0.14
SNP4	A	−0.06 ± 0.10	−0.04 ± 0.04	−11.08 ± 2.77	6.07 ± 2.21	49.79 ± 77.44	0.52 ± 0.28
	P-value	0.58	0.31	<0.0001 ***	0.006***	0.52	0.06
	D	−0.01 ± 0.13	−0.082 ± 0.048	−5.59 ± 3.43	4.27 ± 2.75	131.74 ± 96.98	0.25 ± 0.35
	P-value	0.92	0.08	0.104	0.12	0.17	0.49

A means additive effect, D means dominant effect, single asterisk

(*) shows that the additive and dominance effect of the locus is significant (P < 0.05), while

^***P < 0.001 and

^**P < 0.01

demonstrate that the additive and dominance effect of the locus is highly significant.