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. 2022 Aug 10;600(17):4001–4017. doi: 10.1113/JP282753

Table 2.

Properties of IPSPs in pyramidal cells evoked by optogenetic stimulation of NDNF+ cells

Property Baseline (n = 7) GABAA * (n = 4)
Rise time (ms) 29.9 ± 2.5 25.3 ± 2.5
Decay (τ) (ms) 44.9 ± 3.0
Amplitude (mV) −3.5 ± 0.7 −5.0 ± 1.2 §
Half‐width (ms) 155.7 ± 31.1 72.4 ± 5.4

Data are p means ± SEM. In one cell, GABAA receptors were first blocked with picrotoxin (100 μM), revealing a long‐lasting GABAB‐mediated IPSP with amplitude −1.7 mV and half‐width 239.7 ms (see Fig. 5 Eb).

*

Isolated by application of CGP 55845 (1 μM).

Baseline responses were biphasic.

§

IPSP amplitude increased following application of CGP 55845, likely because of blockade of presynaptic GABAB receptors (Price et al., 2008).