Table 4.

Predictors of persistent peridevice leak at 12 months

	No PDL (N = 60)	New or persistent	p value
		Grade 2–3 PDL (N = 93)
Age, years	$71.4\pm 8.2$	$73.7\pm 8.7$	0.11
Female gender	13 (25)	37 (37)	0.15
Body mass index, kg/m2	26.9 $\pm 3.4$	26.9 $\pm$ 4.5	0.91
Permanent atrial fibrillation	14 (26)	55 (55)	<0.01
Congestive heart failure	8 (15)	19 (19)	0.66
LVEF, %	60 (55–60)	60 (50–60)	0.35
Hypertension	41 (77)	84 (84)	0.38
Diabetes mellitus	9 (17)	17 (17)	0.99
Previous stroke or TIA	23 (43)	46 (46)	0.87
History of bleeding	41 (77)	86 (86)	0.18
Chronic kidney disease, Stage 3–5	8 (15)	3 (3)	0.02
CHA2DS2‐VASc score	3.8 $\pm$ 1.4	4.3 $\pm$ 1.6	0.07
HAS‐BLED score	3.8 $\pm$ 1.1	3.9 $\pm$ 0.8	0.48
Amplatzer Amulet implant	39 (74)	71 (71)	0.85
Implanted device size, mm	23.1 ± 3.9	25 ± 4.2	0.01
LAA orifice diameter, mm	29.1 ± 6.2	31.5 ± 5.3	0.01
LAA landing zone diameter, mm	20.9 ± 3.8	23.1 ± 4.2	<0.01
Time from LAAO to 12‐month CT, days	366 (360–385)	364 (358–379)	0.22

Note: Data are presented as mean ± SD, median (IQR), or frequency (%).

Abbreviations: CT, computed tomography; LAA, left atrial appendage; LAAO, left atrial appendage occlusion; LVEF, left ventricular ejection fraction; TIA, transient ischemic attack.