Skip to main content
. 2022 Aug 2;600(16):3749–3774. doi: 10.1113/JP283017

Figure 4. Effects of digoxin and acute exercise on maximal in vitro 3‐O‐MFPase activity.

Figure 4

The maximal in vitro K+‐stimulated 3‐O‐MFPase activity after 14 days of digoxin (DIG) or placebo (CON) and expressed relative to (A) muscle wet weight and (B) muscle protein content. Biopsies were taken at rest (Rest), after cycling for 10 min at 33% VO2peak and 10 min at 67% VO2peak (67%), immediately following cycling to fatigue at 90% VO2peak (Fatigue) and at 3 h after exercise (+3 h). Data are mean (SD), n = 10; the exact number of data measurement points was 77. Individual data are plotted using different symbols and connected by dashed lines. Time effects are indicated as differences between the times connected by horizontal bar, * P < 0.05, P < 0.01, with exact P values indicated in the Results. No significant digoxin effects (P = 0.287, P = 0.180), or time × treatment interaction (P = 0.610, P = 0.321) were found expressed per g wet weight, or per g protein, respectively.

HHS Vulnerability Disclosure