TABLE 2.
Global patterns of age‐specific incidence rate, male‐to‐female incidence rate ratios and 95% CIs for esophageal squamous cell carcinoma, esophageal adenocarcinoma, gastric cardia cancer and gastric noncardia cancer (2003‐2012)
| Cancer type | Age group | Incidence rate per 100 000 in males (95% CIs) | Incidence rate per 100 000 in females (95% CIs) | Male‐to‐female incidence rate ratios (95% CIs) |
|---|---|---|---|---|
| Esophageal squamous cell carcinoma (ESCC) | 20‐24 | 0.01 (0.01, 0.01) | 0.01 (0.01, 0.01) | 0.98 (0.57, 1.69) |
| 25‐29 | 0.03 (0.02, 0.03) | 0.02 (0.02, 0.03) | 1.31 (0.93, 1.83) | |
| 30‐34 | 0.08 (0.07, 0.09) | 0.06 (0.06, 0.07) | 1.26 (1.04, 1.54) | |
| 35‐39 | 0.28 (0.26, 0.30) | 0.14 (0.13, 0.16) | 1.92 (1.70, 2.16) | |
| 40‐44 | 0.96 (0.92, 0.99) | 0.37 (0.35, 0.39) | 2.57 (2.40, 2.76) | |
| 45‐49 | 2.89 (2.82, 2.95) | 0.80 (0.77, 0.83) | 3.61 (3.44, 3.78) | |
| 50‐54 | 6.42 (6.32, 6.52) | 1.74 (1.69, 1.79) | 3.69 (3.57, 3.81) | |
| 55‐59 | 11.14 (11.00, 11.28) | 2.94 (2.87, 3.01) | 3.78 (3.68, 3.89) | |
| 60‐64 | 16.17 (15.99, 16.36) | 4.24 (4.15, 4.34) | 3.81 (3.72, 3.90) | |
| 65‐69 | 21.22 (20.98, 21.46) | 5.86 (5.75, 5.98) | 3.62 (3.54, 3.70) | |
| 70‐74 | 24.21 (23.93, 24.50) | 7.60 (7.46, 7.75) | 3.19 (3.12, 3.26) | |
| 75‐79 | 24.09 (23.77, 24.43) | 9.06 (8.90, 9.24) | 2.66 (2.60, 2.72) | |
| 80‐84 | 23.34 (22.93, 23.76) | 10.90 (10.68, 11.12) | 2.14 (2.09, 2.20) | |
| 85+ | 21.53 (21.04, 22.03) | 12.48 (12.24, 12.73) | 1.72 (1.67, 1.78) | |
| Esophageal adenocarcinoma (EAC) | 20‐24 | 0.02 (0.01, 0.02) | 0.01 (0.00, 0.01) | 2.92 (1.61, 5.31) |
| 25‐29 | 0.06 (0.05, 0.07) | 0.01 (0.01, 0.01) | 6.23 (4.08, 9.51) | |
| 30‐34 | 0.14 (0.12, 0.15) | 0.03 (0.02, 0.04) | 4.66 (3.67, 5.92) | |
| 35‐39 | 0.38 (0.36, 0.40) | 0.07 (0.06, 0.08) | 5.66 (4.84, 6.60) | |
| 40‐44 | 1.04 (1.00, 1.07) | 0.16 (0.15, 0.18) | 6.44 (5.84, 7.10) | |
| 45‐49 | 2.40 (2.34, 2.45) | 0.32 (0.30, 0.34) | 7.41 (6.92, 7.94) | |
| 50‐54 | 5.00 (4.91, 5.09) | 0.62 (0.59, 0.65) | 8.05 (7.64, 8.47) | |
| 55‐59 | 8.89 (8.76, 9.01) | 1.11 (1.07, 1.15) | 8.00 (7.68, 8.34) | |
| 60‐64 | 13.77 (13.60, 13.95) | 1.72 (1.66, 1.78) | 8.03 (7.74, 8.32) | |
| 65‐69 | 17.68 (17.46, 17.90) | 2.42 (2.34, 2.49) | 7.31 (7.07, 7.56) | |
| 70‐74 | 21.79 (21.52, 22.06) | 3.32 (3.23, 3.42) | 6.56 (6.35, 6.76) | |
| 75‐79 | 26.73 (26.39, 27.08) | 4.63 (4.51, 4.76) | 5.77 (5.60, 5.94) | |
| 80‐84 | 32.86 (32.37, 33.35) | 6.89 (6.71, 7.06) | 4.77 (4.63, 4.91) | |
| 85+ | 34.47 (33.85, 35.10) | 8.84 (8.63, 9.05) | 3.90 (3.79, 4.02) | |
| Gastric cardia cancer (GCC) | 20‐24 | 0.04 (0.03, 0.05) | 0.03 (0.02, 0.03) | 1.49 (1.09, 2.02) |
| 25‐29 | 0.08 (0.07, 0.09) | 0.06 (0.05, 0.07) | 1.32 (1.07, 1.62) | |
| 30‐34 | 0.23 (0.22, 0.25) | 0.13 (0.11, 0.14) | 1.85 (1.62, 2.12) | |
| 35‐39 | 0.52 (0.50, 0.55) | 0.22 (0.20, 0.24) | 2.41 (2.18, 2.66) | |
| 40‐44 | 1.11 (1.07, 1.15) | 0.40 (0.38, 0.43) | 2.76 (2.58, 2.96) | |
| 45‐49 | 2.28 (2.23, 2.34) | 0.63 (0.60, 0.66) | 3.62 (3.43, 3.82) | |
| 50‐54 | 4.16 (4.08, 4.24) | 1.02 (0.98, 1.06) | 4.08 (3.91, 4.26) | |
| 55‐59 | 7.25 (7.14, 7.37) | 1.66 (1.60, 1.71) | 4.38 (4.22, 4.53) | |
| 60‐64 | 10.96 (10.81, 11.12) | 2.43 (2.36, 2.50) | 4.51 (4.37, 4.65) | |
| 65‐69 | 15.70 (15.49, 15.91) | 3.57 (3.48, 3.66) | 4.40 (4.27, 4.53) | |
| 70‐74 | 20.28 (20.02, 20.55) | 4.85 (4.74, 4.97) | 4.18 (4.07, 4.30) | |
| 75‐79 | 23.79 (23.46, 24.12) | 6.05 (5.91, 6.19) | 3.93 (3.83, 4.04) | |
| 80‐84 | 25.21 (24.78, 25.65) | 7.16 (6.98, 7.34) | 3.52 (3.42, 3.63) | |
| 85+ | 22.88 (22.38, 23.40) | 6.98 (6.79, 7.17) | 3.28 (3.17, 3.40) | |
| Gastric noncardia cancer (GNCC) | 20‐24 | 0.22 (0.20, 0.23) | 0.30 (0.28, 0.32) | 0.73 (0.65, 0.81) |
| 25‐29 | 0.61 (0.58, 0.64) | 0.86 (0.82, 0.90) | 0.71 (0.67, 0.76) | |
| 30‐34 | 1.59 (1.54, 1.64) | 2.03 (1.98, 2.09) | 0.78 (0.75, 0.81) | |
| 35‐39 | 3.34 (3.27, 3.41) | 3.38 (3.32, 3.46) | 0.99 (0.96, 1.02) | |
| 40‐44 | 6.73 (6.63, 6.82) | 5.28 (5.19, 5.37) | 1.27 (1.25, 1.30) | |
| 45‐49 | 12.16 (12.03, 12.29) | 7.49 (7.39, 7.60) | 1.62 (1.59, 1.65) | |
| 50‐54 | 20.99 (20.81, 21.17) | 10.28 (10.15, 10.40) | 2.04 (2.01, 2.07) | |
| 55‐59 | 32.17 (31.93, 32.41) | 13.80 (13.65, 13.96) | 2.33 (2.30, 2.36) | |
| 60‐64 | 49.14 (48.81, 49.47) | 19.93 (19.73, 20.13) | 2.47 (2.44, 2.50) | |
| 65‐69 | 73.73 (73.28, 74.18) | 31.04 (30.77, 31.32) | 2.38 (2.35, 2.40) | |
| 70‐74 | 98.87 (98.28, 99.46) | 43.87 (43.52, 44.22) | 2.25 (2.23, 2.28) | |
| 75‐79 | 113.4 (112.7, 114.1) | 53.56 (53.15, 53.99) | 2.12 (2.10, 2.14) | |
| 80‐84 | 122.1 (121.1, 123.1) | 60.86 (60.34, 61.38) | 2.01 (1.98, 2.03) | |
| 85+ | 119.7 (118.5, 120.9) | 65.46 (64.89, 66.03) | 1.83 (1.80, 1.85) |