TABLE 5.
GRADE Certainty of the evidence assessment for at‐home temperature monitoring on incidence of diabetes‐related foot ulcers
| Evidence assessment items | |||||
|---|---|---|---|---|---|
| Studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision |
| 5 | Randomised trials | Serious a | Serious b | Not serious | Not serious |
| Summary of findings | |||||
|---|---|---|---|---|---|
| Number of events | Effect | ||||
| Temperature monitoring | Control | RR (95% CI) | Absolute (95% CI) | Certainty (quality) of evidence | |
| 72/383 (18.8%) | 120/389 (30.8%) | 0.51 (0.31–0.84) | 151 fewer events per 1000 | Low | |
Abbreviations: CI, Confidence intervals; GRADE, Grading of Recommendations, Assessment, Development and Evaluation; RR, relative risk.
a
Downgraded from high to moderate certainty of evidence due to three of the five trials assessed as at high risk of bias.
b
Further downgraded from moderate to low certainty of evidence due to variations in point estimates for the three at high risk of bias trials compared to the two trials deemed to be at lower risk of bias.