TABLE 2.
Scores of social cognition tests in ALS patients and ALS‐CN patients versus controls
| SC subdomain | SC test | Corrected scores, mean ± SD | p | |||
|---|---|---|---|---|---|---|
| ALS patients, n = 83 | ALS‐CN patients, n = 49 | Controls, n = 42 | ALS patients vs. controls | ALS‐CN patients vs. controls | ||
| Facial emotion recognition | EK‐60F | 49.09 ± 8.36 | 48.30 ± 6.21 | 53.61 ± 6.83 | <0.001 a | <0.001 a |
| Happiness | 9.16 ± 1.36 | 9.31 ± 0.95 | 9.45 ± 0.71 | 0.359 | 0.711 | |
| Surprise | 8.33 ± 2.09 | 8.85 ± 1.31 | 9.21 ± 0.84 | 0.078 | 0.357 | |
| Disgust | 6.68 ± 2.06 | 7.26 ± 1.70 | 7.57 ± 1.67 | 0.032 a | 0.390 | |
| Anger | 6.87 ± 2.07 | 7.38 ± 1.80 | 7.76 ± 1.53 | 0.038 a | 0.426 | |
| Fear | 3.83 ± 2.49 | 4.03 ± 2.36 | 5.69 ± 2.50 | <0.001 a | 0.002 a | |
| Sadness | 6.60 ± 2.25 | 7.03 ± 1.91 | 8.50 ± 1.38 | <0.001 a | <0.001 a | |
| Theory of mind | RMET‐36 | 57.66 ± 27.95 | 67.72 ± 24.36 | 78.11 ± 19.62 | <0.001 a | 0.050 |
| SET‐GS | 12.72 ± 4.16 | 14.45 ± 2.96 | 16.54 ± 1.42 | <0.001 a | <0.001 a | |
| SET‐IA | 4.54 ± 1.53 | 5.18 ± 1.17 | 5.66 ± 0.59 | <0.001 a | 0.140 | |
| SET‐CI | 4.48 ± 1.39 | 5.08 ± 0.89 | 5.36 ± 0.78 | <0.001 a | 0.152 | |
| SET‐EA | 4.18 ± 1.61 | 4.80 ± 1.24 | 5.63 ± 0.63 | <0.001 a | 0.002 a | |
Note: Probability values were obtained with Mann–Whitney U test with Bonferroni correction.
Abbreviations: ALS, amyotrophic lateral sclerosis; CI, Causal Inference; CN, cognitively normal; EA, Emotion Attribution; EK‐60F, Ekman 60 Faces Test; GS, Global Score; IA, Intention Attribution; RMET‐36, Reading the Mind in the Eyes Test–36 Faces; SC, social cognition; SET, Story‐Based Empathy Task.
a
Significant p‐values.