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. 2022 Sep 23;12:915498. doi: 10.3389/fonc.2022.915498

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Copyright © 2022 Qiu, Sang, Chen, Zhou, Wang and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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WJR modulated the gut microbiome composition. (A) Bar plot of the phylogenetic composition of gut microbiome at the genus level. (B) PCoA in different groups (A1-4, S1 group; D1-4, S4 group). Alpha diversity of the gut microbiome between the control group and the high dose of the WJR group based on (C) Chao, (D) Shannon and (E) Simpson indices. (F) Wilcoxon rank-sum test was performed for bacterial taxa at the genus level (G) and species level. (H) LEfSe analysis. (I) Taxonomic cladogram from LEfSe. S1, control group; S4, high-dose of WJR group; WJR, Wenzi Jiedu Recipe. ns, not significant.