Table 3.
Multivariable logistic and cox regression analysis showing CCL21 and other variables associated with PAH and predictive of PAH.
| Variable | Associated with PAH | Predictive of PAH | ||
|---|---|---|---|---|
| OR (95% CI) | p-value | HR (95% CI) | p-value | |
| CCL21, per SD | 4.53 (0.98-20.92) | 0.053 | 1.58 (1.02-2.44) | 0.038 |
| ACA | 2.86 (0.44-18.70) | 0.274 | 0.91 (0.37-2.16) | 0.823 |
| sPAP (mmHg) | 1.06 (1.00-1.11) | 0.037 | 1.03 (1.02-1.05) | <0.001 |
| DLCO, % | 0.98 (0.93-1.05) | 0.732 | 0.99 (0.97-1.01) | 0.403 |
PAH, pulmonary arterial hypertension; OR, Odds ratio; CI, confidence interval; HR, Hazard ratio; SD, standard deviation; sPAP, systolic pulmonary artery pressure on echocardiography; DCLO, diffusing capacity of carbon monoxide.