FIGURE 2.

Forest plot of sequence effect (PFS2‐3 and OS2) in different models. Forest plot representing the effect of cabozantinib‐nivolumab (CN) and nivolumab‐cabozantinib (NC) sequences on progression‐free‐survival from line 2 to line 3 (PFS_2‐3) and on overall survival from line 2 (OS₂), according to the following models: all patients (n = 139), all patient with adjustment on propensity score (PrS, n = 139), 1:1 matched population (n = 38), 1:2 matched population (n = 76). Hazard ratio below 1 favors the NC sequence [Color figure can be viewed at wileyonlinelibrary.com]