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. 2022 Jul 20;130(9):568–577. doi: 10.1111/apm.13260

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© 2022 The Authors. APMIS published by John Wiley & Sons Ltd on behalf of Scandinavian Societies for Medical Microbiology and Pathology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Fig. 3 — Heatmap showing the synergistic killing of Candida albicans (SC5314) biofilm by the combination of Darapladib with Caspofungin utilizing the checkerboard microdilution assay (MBKC). Starting concentration of Darapladib is 128 μg/mL and for caspofungin 2 μg/mL. Directional arrows represent a serial doubling reduction from the stated concentration. Growth was measured at 490 nm OD, and values represent median from three biological replicates with three technical repeats. [Colour figure can be viewed at wileyonlinelibrary.com]